Empiric Piperacillin-Tazobactam versus Carbapenems in the Treatment of Bacteraemia Due to Extended-Spectrum Beta-Lactamase-Producing Enterobacteriaceae

TM Ng, WX Khong, PNA Harris, PP De, A Chow… - PloS one, 2016 - journals.plos.org
… and piperacillin-tazobactam. Our results suggested that piperacillin-tazobactam can be as
… We were unable to ascertain if all patients received extended infusions. We attempted to …

Carbapenem therapy is associated with improved survival compared with piperacillin-tazobactam for patients with extended-spectrum β-lactamase bacteremia

PD Tamma, JH Han, C Rock, AD Harris… - Clinical Infectious …, 2015 - academic.oup.com
… The effectiveness of piperacillin-tazobactam (PTZ) for the treatment of extended-spectrum
β-lactamase (ESBL) bacteremia is controversial. We compared 14-day mortality of PTZ vs …

Carbapenems versus piperacillin-tazobactam for bloodstream infections of nonurinary source caused by extended-spectrum beta-lactamase–producing …

H Ofer-Friedman, C Shefler, S Sharma… - infection control & …, 2015 - cambridge.org
… comparing carbapenems to piperacillin-tazobactam among patients … A piperacillin-tazobactam
case was defined as a patient who was treated with ≥2 doses of piperacillintazobactam

Antibiotic policy and prescribing strategies for therapy of extendedspectrum βlactamase‐producing Enterobacteriaceae: the role of piperacillintazobactam

LR Peterson - Clinical Microbiology and Infection, 2008 - Wiley Online Library
… infections caused by extended-spectrum b-lactamase (ESBL)-… to b-lactamb-lactamase
inhibitor combinations, including … the use of more blactamb-lactamase inhibitor compounds that …

Point-counterpoint: piperacillin-tazobactam should be used to treat infections with extended-spectrum-beta-lactamase-positive organisms

AN Schuetz, S Reyes, PD Tamma - Journal of clinical …, 2018 - Am Soc Microbiol
Beta-lactam/beta-lactamase inhibitor combination antimicrobials (… extended-spectrum-beta-lactamase
(ESBL)-producing Gram-negative bacteria (ESBL-GNR). Piperacillin-tazobactam (…

Optimal Piperacillin-Tazobactam Dosing Strategies against Extended-Spectrum-β-Lactamase-Producing Enterobacteriaceae

H Abodakpi, KT Chang, S Gao… - Antimicrobial agents …, 2019 - Am Soc Microbiol
… dosing strategies of piperacillin-tazobactam against ESBL-producing Enterobacteriaceae.
Given the variability of clinical responses to piperacillin-tazobactam, we hypothesized that the …

… controlled trial of piperacillin-tazobactam, cefepime and ertapenem for the treatment of urinary tract infection caused by extended-spectrum beta-lactamase-producing …

YB Seo, J Lee, YK Kim, SS Lee, J Lee, HY Kim… - BMC infectious …, 2017 - Springer
… Carbapenem therapy is associated with improved survival compared with piperacillin-tazobactam
for patients with extended-spectrum beta-lactamase bacteremia. Clin Infect Dis. 2015;…

Is piperacillin-tazobactam effective for the treatment of pyelonephritis caused by extended-spectrum β-lactamase–producing organisms?

SL Sharara, J Amoah, ZD Pana… - Clinical Infectious …, 2020 - academic.oup.com
… Similarly, when discussing the generalizability of their findings, the investigators of the
landmark MERINO trial mention that “whether piperacillin-tazobactam remains effective for urinary …

Piperacillintazobactam: a β-lactam/β-lactamase inhibitor combination

A Gin, L Dilay, JA Karlowsky, A Walkty… - Expert review of anti …, 2007 - Taylor & Francis
… While piperacillintazobactam exhibits a broad spectrum of antibacterial activity, some
Gram-positive bacteria demonstrate intrinsic resistance to the antibiotic. Low affinity of …

Piperacillin/tazobactam as an alternative antibiotic therapy to carbapenems in the treatment of urinary tract infections due to extended-spectrum β-lactamase …

H Guet-Revillet, E Tomini, A Emirian… - International journal of …, 2017 - Elsevier
Piperacillin/tazobactam (TZP) as an alternative treatment to carbapenems for infections
involving extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae (ESBL-PE) …