… resulted in a keen appreciation of the factors that make the development of dengue vaccines
… Rationale underlying dengue vaccine design The design of the dengue vaccine stems from …

… Progress in dengue vaccine development over the last 50 years has been limited. Recently,
a first-generation vaccine has been developed that induces significant but serotype-variable …

… This review provides an update of the latest outcomes of dengue vaccine clinical trials. In
the light of recent progress made in our understanding of dengue pathogenesis and immune …

Dengue has been recognized as one of the most important vector-borne human diseases.
The disease is induced by dengue virus infection resulting from the bite of an infected Aedes …

… Dengue vaccines … dengue vaccine is yet available, several vaccine candidates are under
phases of development, including live attenuated virus vaccines, live chimeric virus vaccines, …

… of dengue symptoms. Although no licensed dengue vaccine is yet available, several vaccine
… , including live attenuated virus vaccines, live chimeric virus vaccines, inactivated virus …

… There is no licensed dengue vaccine and no prophylactic or therapeutic dengue drug (ie, …
tetravalent dengue vaccine is the best strategy for reducing the global dengue burden. …

… has been an ambitious task due to the presence of four different dengue serotypes capable
… challenges in the construction of a dengue vaccine and the current status of the vaccine …

… dengue vaccine development and advances. Moreover, we review some of the factors affecting
vaccine responses, such as the pre-vaccination … progression of the self-limited dengue …

… Additional challenges are posed by the lack of an adequate animal … challenges, vaccine
development has made remarkable progress in recent years, and the current dengue vaccine …