Heated humidified high-flow nasal cannula oxygen after thoracic surgery—a randomized prospective clinical pilot trial

J Brainard, BK Scott, BL Sullivan… - Journal of critical …, 2017 - Elsevier
Background Thoracic surgery patients are at high-risk for adverse pulmonary outcomes.
Heated humidified high-flow nasal cannula oxygen (HHFNC O 2) may decrease such
events. We hypothesized that patients randomized to prophylactic HHFNC O 2 would
develop fewer pulmonary complications compared to conventional O 2 therapy. Methods
and patients Fifty-one patients were randomized to HHFNC O 2 vs. conventional O 2. The
primary outcome was a composite of postoperative pulmonary complications. Secondary …

Humidified high-flow nasal cannula oxygen for bronchiolitis: should we go with the flow?

AO Mace, J Gibbons, A Schultz, G Knight… - Archives of disease in …, 2018 - adc.bmj.com
Despite living in an era of evidence-based medicine and austerity, where every health dollar
must be justified, the use of humidified high-flow nasal cannula oxygen (HFNC) in children
with bronchiolitis has become increasingly prevalent, 1 with limited evidence to substantiate
its clinical benefit or economic worth. Current National Institute for Health and Care
Excellence (NICE 2015) guidelines for bronchiolitis state that 'the use of this medical device
is becoming widespread without demonstration of additional efficacy'. Recent studies by …
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