… In this multicentre study we aimed to assess which clinical and environmental variables …
from adult CIS to CDMS using the largest cohort of adult CIS cases studied to date (n = 1047). …

… considered in developing the study design of the Australian Multicentre Study of Environment
and Immune Function (the Ausimmune Study) (see Box 1). We first consider the choice of …

… walking speed and walking distance in multiple sclerosis (MS) patients with diverse ambulation
status. Methods: A cross-sectional multicentre study design was applied. Ambulatory MS …

… We performed a multicentre retrospective study to describe … , it is easier to make an early
diagnosis of multiple sclerosis (MS) [1]. … We designed a multicentre, retrospective study on MS …

… The dose used in oncology is much higher than in multiple sclerosis studies and the main …
in the present study (about 70 mg/M2). No cases were seen in the present study despite very …

… study the effect of natural menopause on multiple sclerosis clinical course. Methods This was
an observational, retrospective, multicentre, cohort study… We included multiple sclerosis (MS…

… If a treatment effect is shown in a multi-centre study, the generalisability increases. It has,
nevertheless, been reported that multi-centre trials show fewer treatment effects compared with …

INTRODUCTION: Multiple sclerosis (MS) is considered to be a low prevalence disease in
Mexico; its characteristics have been described in isolated studies in small populations …

… in a large cohort of patients with multiple sclerosis with different ages and disease clinical
phenotypes, and we evaluated its feasibility and clinical relevance in a multicentre setting. …

… Following a previous study assessing the safety of interferon beta (IFNB) pregnancy exposure
in multiple sclerosis (MS), we aimed to assess pregnancy and fetal outcomes after in utero …