… after immunization for isotype-switched antigen-specific B cells with cell surface characteristics
of memory B cells. NP + IgG1 + blood B cells accumulate V H gene somatic mutations …

… B cell memory is retained in the form of memory B cells, GC B cells, and GC phenotype B cells
… Eight to 10 weeks after primary immunization, we boosted these animals in the ipsilateral …

… -dependent antigen, we enumerated NP-specific CD38 dull B cells in the spleen of
C57BL/6 mice after immunization with alum-precipitated NP-CG. As shown in Fig. 1(A), a small …

… response observed in this study is similar to the response observed in a study assessing
the B-cell response to primary immunization with serogroup C meningococcal conjugate …

… exhibit an accelerated contraction after certain infections in B-cell-deficient mice. Here,
we find that B cells significantly enhance primary CD8 T cell responses after vaccination. …

… This is comparable to the fate chosen by switched B cells in the primary GC response (54–58).
However, these observations may not be exclusively dependent on immunoglobulin …

… We hypothesize that individuals with good E47/AID/CSR will have good primary and
secondary antibody responses and those with reduced CSR will have defects in the generation of …

… this hypothesis by studying the phenotype of memory B cells, defined by adoptive transfer
of … after primary or secondary antigen exposure. We employed fluorescence-activated cell …

… the memory B cells pool can deal with variant viruses. Despite such progress, efforts to develop
vaccines that induce broadly protective memory B cells … In the primary GC, B cell clones …

… -lived plasma cells and memory B cells from the naive B cell repertoire in the primary response
to … extensive SHM and differentiated into memory B cells following a single immunization. …