A large gene family in fission yeast encodes spore killers that subvert Mendel's law

W Hu, ZD Jiang, F Suo, JX Zheng, WZ He, LL Du - Elife, 2017 - elifesciences.org
… Abstract Spore killers in fungi are selfish genetic elements … Here, we discover two spore
killers from a natural isolate of … two active spore killers, which both belong to the wtf gene family. …

Molecular mechanisms and evolutionary consequences of spore killers in ascomycetes

S Zanders, H Johannesson - Microbiology and Molecular Biology …, 2021 - Am Soc Microbiol
genes of the Spok gene family underlie the Psk spore killers (49), and the relationship
between the Spok gene family … The wtf genes comprise a large gene family, originally identified …

The spore killers, fungal meiotic driver elements

AA Vogan, I Martinossi-Allibert, SL Ament-Velásquez… - Mycologia, 2022 - Taylor & Francis
… fungi for which new data are currently emerging at a high pace: the spore killers Table 1 . …
Although we currently only have two examples of spore killing gene family expansion, they …

[HTML][HTML] Proliferation and dissemination of killer meiotic drive loci

EC Lai, AA Vogan - Current Opinion in Genetics & Development, 2023 - Elsevier
spore killers reveal that numerous systems are enacted by single genes, and similar molecular
genetic … evolutionary relationship between this gene family and these massive TEs, or …

Killer Meiotic Drive and Dynamic Evolution of the wtf Gene Family

MT Eickbush, JM Young… - Molecular Biology and …, 2019 - academic.oup.com
… Our mate-pair pileup approach could also miss additional wtf gene copies if they were
found within larger recently duplicated regions of the genome. To look for such wtf …

On the mechanistic basis of killer meiotic drive in fungi

SJ Saupe, H Johannesson - Annual Review of Microbiology, 2022 - annualreviews.org
… the study of spore killers in … gene family of 25 members frequently associated with transposons
(wtf stands for with Tf transposons) had previously been noted as the largest gene family

A natural fungal gene drive enacts killing via DNA disruption

AS Urquhart, DM Gardiner - Mbio, 2023 - Am Soc Microbiol
… of the mechanisms underlying spore killers are limited. In … them into high concentrations
of glucose to suppress gene … action described here will be conserved in this gene family. …

Making a murderer: the evolutionary framing of hybrid gamete-killers

AL Sweigart, Y Brandvain, L Fishman - Trends in Genetics, 2019 - cell.com
Recent molecular investigations of hybrid incompatibilities have revealed fascinating patterns
of genetic interactions that have been interpreted as the remnants of a history of selfish …

A family of killers

M De Carvalho, SE Zanders - Elife, 2019 - elifesciences.org
… Spok genes (Spok3 and Spok4) that are both spore killers. … Here we show that the Spok
gene family underlies the Psks. … several members of the large gene family known as odorant …

[PDF][PDF] Invasion and maintenance of spore killers in populations of

CR Vogan, H Johannesson - 2020 - scholar.archive.org
… We first assume 146 that the population is sufficiently large that … We then relax the assumption
of infinitely large population … costs affect spore killers very little 343 during early invasion. …