BRAF Mutation in Papillary Thyroid Cancer: Pathogenic Role, Molecular Bases, and Clinical Implications
M Xing - Endocrine reviews, 2007 - academic.oup.com
… of thyroid cancer are papillary thyroid cancer (PTC), follicular thyroid cancer (FTC), and
anaplastic thyroid cancer (… of this mutation, such as thyroid cancer (13), the focus of this review. …
anaplastic thyroid cancer (… of this mutation, such as thyroid cancer (13), the focus of this review. …
BRAF mutation predicts a poorer clinical prognosis for papillary thyroid cancer
M Xing, WH Westra, RP Tufano, Y Cohen… - The Journal of …, 2005 - academic.oup.com
… shown that this BRAF mutation occurs in papillary thyroid cancer (PTC) with a … mutation
occurs exclusively in PTC and PTC-derived anaplastic thyroid cancers but not in normal thyroid …
occurs exclusively in PTC and PTC-derived anaplastic thyroid cancers but not in normal thyroid …
Association between BRAF V600E mutation and mortality in patients with papillary thyroid cancer
M Xing, AS Alzahrani, KA Carson, D Viola, R Elisei… - Jama, 2013 - jamanetwork.com
… BRAF V600E is a prominent oncogene in papillary thyroid cancer (PTC), but its role in
PTC-… of the BRAF V600E mutation was significantly associated with increased cancer-related …
PTC-… of the BRAF V600E mutation was significantly associated with increased cancer-related …
[HTML][HTML] Association between BRAF V600E mutation and recurrence of papillary thyroid cancer
M Xing, AS Alzahrani, KA Carson… - Journal of clinical …, 2015 - ncbi.nlm.nih.gov
… Kaplan-Meier survival curves of effect of BRAF V600E mutation status on disease
recurrence–free probability in patients with various types of papillary thyroid cancer (PTC) …
recurrence–free probability in patients with various types of papillary thyroid cancer (PTC) …
[PDF][PDF] The relation between BRAFV600E mutation and clinicopathological characteristics of papillary thyroid cancer
… Aim BRAF mutation inhibits many … papillary thyroid cancer (PTC), giving it more aggressive
clinical characteristics. In this study, we aimed to evaluate the effect of BRAF V600E mutation …
clinical characteristics. In this study, we aimed to evaluate the effect of BRAF V600E mutation …
[PDF][PDF] Evolution and impact of subclonal mutations in papillary thyroid cancer
… Unlike many cancers, the pattern of tumor evolution in papillary thyroid cancer (PTC) and
its … and spatial framework within which subclonal mutations catalyze tumor evolution and its …
its … and spatial framework within which subclonal mutations catalyze tumor evolution and its …
Prognostic utility of BRAF mutation in papillary thyroid cancer
M Xing - Molecular and cellular endocrinology, 2010 - Elsevier
… The vast majority of thyroid cancers originate from follicular epithelial cells, which are … as
papillary thyroid cancer (PTC), follicular thyroid cancer (FTC), and anaplastic thyroid cancer (…
papillary thyroid cancer (PTC), follicular thyroid cancer (FTC), and anaplastic thyroid cancer (…
BRAF mutation in papillary thyroid cancer and its value in tailoring initial treatment: a systematic review and meta-analysis
… ) mutation in exon 15 of the BRAF gene has been noted to be a putative prognostic marker
of the most prevalent form of thyroid cancer, papillary thyroid cancer (… of BRAF mutation with …
of the most prevalent form of thyroid cancer, papillary thyroid cancer (… of BRAF mutation with …
Clinical Implication of Hot Spot BRAF Mutation, V599E, in Papillary Thyroid Cancers
H Namba, M Nakashima, T Hayashi… - The Journal of …, 2003 - academic.oup.com
… cancers. The aim of the present study was to determine the frequency of BRAF mutations in
thyroid cancer … six human thyroid cancer cell lines and 207 paraffin-embedded thyroid tumor …
thyroid cancer … six human thyroid cancer cell lines and 207 paraffin-embedded thyroid tumor …
The association of the BRAFV600E mutation with prognostic factors and poor clinical outcome in papillary thyroid cancer: A meta‐analysis
… The majority of the incidences of thyroid cancer are papillary thyroid cancer (PTC), which
accounts for approximately 85%.3 Although most PTC patients have excellent overall survival, …
accounts for approximately 85%.3 Although most PTC patients have excellent overall survival, …
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