BRAF Mutation in Papillary Thyroid Cancer: Pathogenic Role, Molecular Bases, and Clinical Implications

M Xing - Endocrine reviews, 2007 - academic.oup.com
… of thyroid cancer are papillary thyroid cancer (PTC), follicular thyroid cancer (FTC), and
anaplastic thyroid cancer (… of this mutation, such as thyroid cancer (13), the focus of this review. …

BRAF mutation predicts a poorer clinical prognosis for papillary thyroid cancer

M Xing, WH Westra, RP Tufano, Y Cohen… - The Journal of …, 2005 - academic.oup.com
… shown that this BRAF mutation occurs in papillary thyroid cancer (PTC) with a … mutation
occurs exclusively in PTC and PTC-derived anaplastic thyroid cancers but not in normal thyroid

Association between BRAF V600E mutation and mortality in patients with papillary thyroid cancer

M Xing, AS Alzahrani, KA Carson, D Viola, R Elisei… - Jama, 2013 - jamanetwork.com
… BRAF V600E is a prominent oncogene in papillary thyroid cancer (PTC), but its role in
PTC-… of the BRAF V600E mutation was significantly associated with increased cancer-related …

[HTML][HTML] Association between BRAF V600E mutation and recurrence of papillary thyroid cancer

M Xing, AS Alzahrani, KA Carson… - Journal of clinical …, 2015 - ncbi.nlm.nih.gov
… Kaplan-Meier survival curves of effect of BRAF V600E mutation status on disease
recurrence–free probability in patients with various types of papillary thyroid cancer (PTC) …

[PDF][PDF] The relation between BRAFV600E mutation and clinicopathological characteristics of papillary thyroid cancer

M Celik, BY Bulbul, S Ayturk, Y Durmus, H Gurkan… - Med Glas (Zenica), 2020 - ljkzedo.ba
… Aim BRAF mutation inhibits many … papillary thyroid cancer (PTC), giving it more aggressive
clinical characteristics. In this study, we aimed to evaluate the effect of BRAF V600E mutation

[PDF][PDF] Evolution and impact of subclonal mutations in papillary thyroid cancer

T Masoodi, AK Siraj, S Siraj, S Azam, Z Qadri… - The American Journal of …, 2019 - cell.com
… Unlike many cancers, the pattern of tumor evolution in papillary thyroid cancer (PTC) and
its … and spatial framework within which subclonal mutations catalyze tumor evolution and its …

Prognostic utility of BRAF mutation in papillary thyroid cancer

M Xing - Molecular and cellular endocrinology, 2010 - Elsevier
… The vast majority of thyroid cancers originate from follicular epithelial cells, which are … as
papillary thyroid cancer (PTC), follicular thyroid cancer (FTC), and anaplastic thyroid cancer (…

BRAF mutation in papillary thyroid cancer and its value in tailoring initial treatment: a systematic review and meta-analysis

RP Tufano, GV Teixeira, J Bishop, KA Carson, M Xing - Medicine, 2012 - journals.lww.com
… ) mutation in exon 15 of the BRAF gene has been noted to be a putative prognostic marker
of the most prevalent form of thyroid cancer, papillary thyroid cancer (… of BRAF mutation with …

Clinical Implication of Hot Spot BRAF Mutation, V599E, in Papillary Thyroid Cancers

H Namba, M Nakashima, T Hayashi… - The Journal of …, 2003 - academic.oup.com
cancers. The aim of the present study was to determine the frequency of BRAF mutations in
thyroid cancer … six human thyroid cancer cell lines and 207 paraffin-embedded thyroid tumor …

The association of the BRAFV600E mutation with prognostic factors and poor clinical outcome in papillary thyroid cancer: A meta‐analysis

TH Kim, YJ Park, JA Lim, HY Ahn, EK Lee, YJ Lee… - Cancer, 2012 - Wiley Online Library
… The majority of the incidences of thyroid cancer are papillary thyroid cancer (PTC), which
accounts for approximately 85%.3 Although most PTC patients have excellent overall survival, …