… of a peripheral opioid effect on bladder function. The results suggest that MNTX should
be evaluated as a potential treatment for patients with opioid-induced urinary retention. …

… of opioid production and the release of endogenous opioids from … on the development of new
peripheral opioid agonists as well as … peripheral analgesia with reduced central side effects …

… types of peripheral opioid … , peripheral opioid analgesic effects require more extensively
controlled clinical studies in view of the potential avoidance of centrally mediated adverse effects …

… mechanisms underlying peripheral opioid analgesic effects such as localization, trafficking
and function of peripheral opioid receptors and the production and release of opioid peptides …

… peripheral analgesic effects of M6G in the present study. To account for the differences in the
number of peripheral opioid … The absence or presence of CNS opioid effects was monitored …

… Thus, our aim was to comprehensively evaluate the peripheral antinociceptive effects of μ-,
δ- and κ-opioid receptor agonists after their local (i.pl.) administration in two distinct rodent …

… Consistent with our present findings, peripheral opioid antinociceptive effects have been
reported at very early stages of different inflammatory conditions (reviews in Barber and …

… active opioids have anti-inflammatory effects and … opioid receptors and their ligands in
peripheral tissues. We will then focus on mechanisms and the functional role of peripheral opioids …

… Peripheral opioid antagonists may play a role in elucidating the mechanism responsible
for the urodynamic effects of opioids. There are no studies of the effect of peripheral opioid …

… A prerequisite for the manifestation of such peripheral effects … opioid receptor types, the
role of endogenous opioid peptides and the intrinsic mechanisms involved in peripheral opioid …