MAPK pathways in radiation responses
P Dent, A Yacoub, PB Fisher, MP Hagan, S Grant - Oncogene, 2003 - nature.com
… the JNK and P38 MAPK pathways. The … responses of MAPK pathways in cells and,
consequently, of bystander cells. Thus, the ability of radiation to activate MAPK signaling pathways …
consequently, of bystander cells. Thus, the ability of radiation to activate MAPK signaling pathways …
The MAPK pathway across different malignancies: a new perspective
M Burotto, VL Chiou, JM Lee, EC Kohn - Cancer, 2014 - Wiley Online Library
… in MAPK/ERK pathway components… MAPK and other pathways to optimize the treatment of
many tumor types. Therapies targeted toward MAPK/ERK components have various response …
many tumor types. Therapies targeted toward MAPK/ERK components have various response …
[HTML][HTML] Understanding MAPK signaling pathways in apoptosis
J Yue, JM López - International journal of molecular sciences, 2020 - mdpi.com
… We also describe the basic signaling properties of MAPKs (ultrasensitivity, hysteresis, digital
response), and the presence of different positive feedback loops in apoptosis. We provide a …
response), and the presence of different positive feedback loops in apoptosis. We provide a …
[HTML][HTML] The role of MAPK signalling pathways in the response to endoplasmic reticulum stress
NJ Darling, SJ Cook - Biochimica et Biophysica Acta (BBA)-Molecular Cell …, 2014 - Elsevier
… survival or death responses following a … of MAPK signalling pathways in response to ER
stress. In addition, we highlight components of the UPR that are modulated in response to MAPK …
stress. In addition, we highlight components of the UPR that are modulated in response to MAPK …
[HTML][HTML] TRAF6 autoubiquitination-independent activation of the NFκB and MAPK pathways in response to IL-1 and RANKL
MC Walsh, GK Kim, PL Maurizio, EE Molnar, Y Choi - PloS one, 2008 - journals.plos.org
The adapter protein TRAF6 is critical for mediating signal transduction from members of the
IL-1R/TLR and TNFR superfamilies. The TRAF6 RING finger domain functions as an …
IL-1R/TLR and TNFR superfamilies. The TRAF6 RING finger domain functions as an …
[HTML][HTML] Sustained activation of JNK/p38 MAPK pathways in response to cisplatin leads to Fas ligand induction and cell death in ovarian carcinoma cells
A Mansouri, LD Ridgway, AL Korapati, Q Zhang… - Journal of Biological …, 2003 - ASBMB
… MAPK pathways correlated with CDDP-induced apoptosis. A strong sustained activation of
both pathways … ; this activation of both JNK and p38 MAPK in CDDP-sensitive cells correlated …
both pathways … ; this activation of both JNK and p38 MAPK in CDDP-sensitive cells correlated …
[HTML][HTML] Microphthalmia transcription factor is a target of the p38 MAPK pathway in response to receptor activator of NF-κB ligand signaling
… -derived precursor cells blocked for p38 MAPK activity and the mi/mi osteoclasts-… MAPK in
osteoclasts. In this study, we investigate whether MITF is a potential target of the p38 MAPK in …
osteoclasts. In this study, we investigate whether MITF is a potential target of the p38 MAPK in …
MAPK machinery in plants: recognition and response to different stresses through multiple signal transduction pathways
… MAP kinase pathways have revealed the specificity of the kinases in the cascade, signal
transduction patterns, identity of pathway … of MAPK pathway modules in plant stress signaling. …
transduction patterns, identity of pathway … of MAPK pathway modules in plant stress signaling. …
[HTML][HTML] MAP kinase pathways
MH Cobb - Progress in biophysics and molecular biology, 1999 - Elsevier
… , amplify signals, and allow for a variety of response patterns. Subcellular localization of …
ligand-specific responses. Recent findings on these properties of MAP kinase cascades are the …
ligand-specific responses. Recent findings on these properties of MAP kinase cascades are the …
MAP kinase pathways activated by stress: the p38 MAPK pathway
T Obata, GE Brown, MB Yaffe - Critical care medicine, 2000 - journals.lww.com
… MAPK-dependent host response in at least two ways. First, some bacteria blunt the host
response by blocking p38 MAPK … the host response via inhibition of the p38 MAPK pathway may …
response by blocking p38 MAPK … the host response via inhibition of the p38 MAPK pathway may …
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