Genotyping HLA alleles to predict the development of Severe cutaneous adverse drug reactions (SCARs): state-of-the-art

T Jantararoungtong, T Tempark… - Expert Opinion on …, 2021 - Taylor & Francis
… Studies have revealed the interaction between the highly polymorphic human leukocyte
antigen (HLA) and drugs, and HLA genotypes have been implicated in explaining the variability …

[HTML][HTML] A Comprehensive Review of HLA and Severe Cutaneous Adverse Drug Reactions: Implication for Clinical Pharmacogenomics and Precision Medicine

C Kloypan, N Koomdee, P Satapornpong, T Tempark… - Pharmaceuticals, 2021 - mdpi.com
… drug hypersensitivity reactions as well. … severe cutaneous adverse drug reactions (SCARs)
such as Stevens–Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), drug reaction

Carbamazepine-induced severe cutaneous adverse reactions and HLA genotypes in Koreans

…, Adverse Drug Reaction Research Group in Korea - Epilepsy research, 2011 - Elsevier
… and carbamazepine-induced severe cutaneous adverse reaction (SCAR) in Koreans. …
reactions (Leeder, 1998). It occasionally causes a severe cutaneous adverse reaction (SCAR), …

Association of HLA genotypes with phenytoin induced severe cutaneous adverse drug reactions in Thai children

W Manuyakorn, P Likkasittipan, S Wattanapokayakit… - Epilepsy Research, 2020 - Elsevier
severe cutaneous adverse drug reactions (SCARs) in children. SCARs, including drug reaction
… This study was to investigate the association between variations of HLA genotypes and …

[HTML][HTML] An update on HLA alleles associated with adverse drug reactions

I Fricke-Galindo, A LLerena… - Drug Metabolism and …, 2017 - degruyter.com
cutaneous adverse drug reactions (cADRs); in this case, the drug may not directly bind to
HLA, and this hypothesis elucidates in part the association of HLA-B*57:01 and abacavir-…

[HTML][HTML] Genetic markers of severe cutaneous adverse reactions

JW Jung, JY Kim, IW Park, BW Choi… - The Korean Journal of …, 2018 - ncbi.nlm.nih.gov
… Specific HLA genotypes play an important role in the development of SCARs [8]. In 1987,
Roujeau et al. [9] reported that HLA-A29, HLA-B12, and HLA-DR7 were associated with …

Dapsone-induced severe cutaneous adverse drug reactions are strongly linked with HLA-B* 13: 01 allele in the Thai population

T Tempark, P Satapornpong, P Rerknimitr… - Pharmacogenetics …, 2017 - journals.lww.com
… The aim of this study is to investigate whether there is an association between HLA genotypes
and dapsone-induced severe cutaneous adverse reactions (SCARs) in Thai nonleprosy …

HLA-A* 31: 01 and different types of carbamazepine-induced severe cutaneous adverse reactions: an international study and meta-analysis

E Genin, DP Chen, SI Hung, P Sekula… - The …, 2014 - nature.com
… HLA-B*5801 allele as a genetic marker for severe cutaneous adverse reactions caused
by … Carbamazepine-induced severe cutaneous adverse reactions and HLA genotypes in …

Reducing severe cutaneous adverse and type B adverse drug reactions using pre‐stored human leukocyte antigen genotypes

KH Lee, DY Kang, HH Kim, YJ Kim… - Clinical and …, 2022 - Wiley Online Library
… First, the HLA genotypes selected in this study were obtained from results accumulated
over a long period using various HLA testing methods. Therefore, the results of the lower …

Association between HLA-B* 1301 and dapsone-induced cutaneous adverse drug reactions: a systematic review and meta-analysis

W Tangamornsuksan, M Lohitnavy - JAMA dermatology, 2018 - jamanetwork.com
… Our search terms were combinations of keywords and synonyms for HLA genotypes and
dapsone without language or study-design restrictions. Only human studies were included. …