Antioxidant response element

AK Jaiswal - Biochemical pharmacology, 1994 - Elsevier
Antioxidant response element (ARE?), also referred to as electrophile response element (EpRE),
has been found in the promoter regions of rat and human NAD (P) H: quinone …

[HTML][HTML] Antioxidant response elements: Discovery, classes, regulation and potential applications

A Raghunath, K Sundarraj, R Nagarajan, F Arfuso… - Redox biology, 2018 - Elsevier
response elements (AREs), which play a critical role in redox homeostasis. Though … activator
screening. The complexity of AREs is brought by the presence of other regulatory elements

The Nrf2-antioxidant response element signaling pathway and its activation by oxidative stress

T Nguyen, P Nioi, CB Pickett - Journal of biological chemistry, 2009 - ASBMB
… is activation of the Nrf2-antioxidant response element signaling … antioxidant capacity. At
the molecular level, however, the regulatory mechanisms involved in mediating Nrf2 activation

Transcriptional regulation of the antioxidant response element: activation by Nrf2 and repression by MafK

T Nguyen, HC Huang, CB Pickett - Journal of Biological Chemistry, 2000 - ASBMB
… The antioxidant response element (ARE) mediates the transcriptional activation of many …
The antioxidant response element (ARE) 1 is a uniquecis-acting regulatory sequence found in …

A genomic screen for activators of the antioxidant response element

Y Liu, JT Kern, JR Walker, JA Johnson… - Proceedings of the …, 2007 - National Acad Sciences
… In humans, the antioxidant response element (ARE) regulates the expression of a number
of cytoprotective antioxidant enzymes and scavengers, which contribute to the endogenous …

Regulatory mechanisms controlling gene expression mediated by the antioxidant response element

T Nguyen, PJ Sherratt, CB Pickett - Annual review of …, 2003 - annualreviews.org
antioxidant response element (ARE) is a cis-acting enhancer sequence that mediates
transcriptional activation … enhancer region known as the xenobiotic response element (XRE) (13, …

Activation of mitogen-activated protein kinase pathways induces antioxidant response element-mediated gene expression via a Nrf2-dependent mechanism

R Yu, C Chen, YY Mo, V Hebbar, ED Owuor… - Journal of Biological …, 2000 - ASBMB
Antioxidant response element (ARE) regulates the induction of a number of cellular antioxidant
… However, the signaling pathways that lead to ARE activation remain unknown. Here, we …

Nrf1 and Nrf2 play distinct roles in activation of antioxidant response element-dependent genes

M Ohtsuji, F Katsuoka, A Kobayashi, H Aburatani… - Journal of Biological …, 2008 - ASBMB
… Among CNC family members, Nrf2 is known to regulate a battery of antioxidant and
xenobiotic-metabolizing enzyme genes through the antioxidant response element (ARE). Although …

Genetic evidence that small maf proteins are essential for the activation of antioxidant response element-dependent genes

F Katsuoka, H Motohashi, T Ishii… - … and cellular biology, 2005 - Am Soc Microbiol
… While small Maf proteins have been suggested to be essential for the Nrf2-mediated activation
of antioxidant response element (ARE)-dependent genes, the extent of their requirement …

Carotenoids activate the antioxidant response element transcription system

A Ben-Dor, M Steiner, L Gheber, M Danilenko… - Molecular Cancer …, 2005 - AACR
… (22), may function as anticancer agents by activating this transcription system. Carotenoids,
activation of the ARE transcription system. In the current study, we examined the activation of …