[HTML][HTML] A phase II study of erlotinib as initial treatment for patients with stage IIIB-IV non-small cell lung cancer

W Akerley, KM Boucher, JS Bentz, K Arbogast… - Journal of Thoracic …, 2009 - Elsevier
… stable disease, erlotinib was also … III study of erlotinib in patients with NSCLC previously
treated with one or two prior cytotoxic chemotherapy regimens, patients treated with erlotinib

Randomized phase II study of gefitinib versus erlotinib in patients with advanced non-small cell lung cancer who failed previous chemotherapy

ST Kim, JE Uhm, J Lee, J Sun, I Sohn, SW Kim… - Lung Cancer, 2012 - Elsevier
III trial to directly compare the efficacy and toxicity between gefitinib and erlotinib in an
enriched patient … In summary, this study demonstrated that both gefitinib and erlotinib showed …

A phase III randomised controlled trial of erlotinib vs gefitinib in advanced non-small cell lung cancer with EGFR mutations

JJ Yang, Q Zhou, HH Yan, XC Zhang, HJ Chen… - British journal of …, 2017 - nature.com
study was the first head-to-head phase III randomised controlled trial comparing erlotinib with
… The results did not support the hypothesis described in the study design, namely, that the …

Adjuvant erlotinib versus placebo in patients with stage IB-IIIA non–small-cell lung cancer (RADIANT): A randomized, double-blind, phase III trial

K Kelly, NK Altorki, WEE Eberhardt… - Journal of Clinical …, 2015 - escholarship.org
… , this study did not show a DFS benefit for erlotinib in patients … , the study failed to demonstrate
a DFS benefit for erlotinib in … A phase III US intergroup trial of adjuvant erlotinib in EGFRm-…

Erlotinib as maintenance treatment in advanced non-small-cell lung cancer: a multicentre, randomised, placebo-controlled phase 3 study

F Cappuzzo, T Ciuleanu, L Stelmakh, S Cicenas… - The lancet …, 2010 - thelancet.com
… ] of 443 patients vs none of 445). Serious adverse events were reported in 47 patients (11%)
on erlotinib compared with 34 patients (… Phase III study of immediate compared with delayed …

[HTML][HTML] SELECT: a phase II trial of adjuvant erlotinib in patients with resected epidermal growth factor receptor–mutant non–small-cell lung cancer

NA Pennell, JW Neal, JE Chaft, CG Azzoli… - Journal of Clinical …, 2019 - ncbi.nlm.nih.gov
… The reported 2-year DFS was 89% in the patients who received … higher percentage of patients
with stage II and III disease in the … During the conduct of our study, two phase III trials were …

Erlotinib for frontline treatment of advanced non–small cell lung cancer: a phase II study

G Giaccone, M Gallegos Ruiz, T Le Chevalier… - Clinical Cancer …, 2006 - AACR
… II study of single-agent erlotinib as first-line therapy in patientsstudies on tumor samples of
patients entered in the study to … The promising efficacy of erlotinib monotherapy in this study

[HTML][HTML] Final overall survival results from a randomised, phase III study of erlotinib versus chemotherapy as first-line treatment of EGFR mutation-positive advanced …

C Zhou, YL Wu, G Chen, J Feng, XQ Liu, C Wang… - Annals of …, 2015 - Elsevier
… In the current study, ∼40% of erlotinib-treated patients in the overall population and exon …
receive any post-study treatment. On the other hand, almost 80% of patients who received first-…

SEARCH: a phase III, randomized, double-blind, placebo-controlled trial of sorafenib plus erlotinib in patients with advanced hepatocellular carcinoma

AX Zhu, O Rosmorduc, TRJ Evans, PJ Ross… - Journal of Clinical …, 2015 - ascopubs.org
… of erlotinib improves the efficacy of sorafenib in patients with advanced HCC, a phase III trial
… efficacy and safety of first-line sorafenib/erlotinib with sorafenib/placebo in these patients. …

… A double-blind, randomized, phase III study of maintenance erlotinib versus placebo following nonprogression with first-line platinum-based chemotherapy in patients …

F Cappuzzo, T Ciuleanu, L Stelmakh… - Journal of Clinical …, 2009 - ascopubs.org
8001 Background: Erlotinib (E), a small-molecule EGFR TKI, is proven to extend survival
versus placebo (P) in 2nd/3rd-line advanced NSCLC. The phase III SATURN study (BO18192) …