[HTML][HTML] Targeting signal transduction as a strategy to treat inflammatory diseases
LAJ O'Neill - Nature reviews Drug discovery, 2006 - nature.com
… of inflammatory diseases, and the quality of one target relative to another remains difficult
to assess. A drug that targets signalling might be attractive, however, as it could potentially …
to assess. A drug that targets signalling might be attractive, however, as it could potentially …
[HTML][HTML] Targeting macrophages as a potential therapeutic intervention: impact on inflammatory diseases and cancer
M Ponzoni, F Pastorino, D Di Paolo, P Perri… - International journal of …, 2018 - mdpi.com
… In this review, we focus on macrophage targeting, based on the results so far obtained in
preclinical models of inflammatory diseases and cancer. Pros and cons of these therapeutic …
preclinical models of inflammatory diseases and cancer. Pros and cons of these therapeutic …
Targeting selectins for the treatment of inflammatory diseases
D Impellizzeri, S Cuzzocrea - Expert opinion on therapeutic targets, 2014 - Taylor & Francis
… to sites of inflammation is a crucial step in the pathogenesis of acute and chronic forms of
inflammatory diseases including hypersensitivity reactions, autoimmune diseases and ischemia…
inflammatory diseases including hypersensitivity reactions, autoimmune diseases and ischemia…
Drug targeting systems for inflammatory disease: one for all, all for one
BJ Crielaard, T Lammers, RM Schiffelers… - Journal of controlled …, 2012 - Elsevier
… As discussed in this review, many inflammatory diseases, including cancer, may be targeted
… and upregulation of target-specific receptors, and drugs, such as anti-inflammatory and anti-…
… and upregulation of target-specific receptors, and drugs, such as anti-inflammatory and anti-…
Therapeutic targeting of Toll-like receptors for infectious and inflammatory diseases and cancer
… interested in inflammation), previously thought it to be relatively crude, nonspecific, and
somewhat unpromising for specific therapeutic targets for infectious and inflammatory diseases. …
somewhat unpromising for specific therapeutic targets for infectious and inflammatory diseases. …
Cytokines as therapeutic targets in rheumatoid arthritis and other inflammatory diseases
S Siebert, A Tsoukas, J Robertson, I McInnes - Pharmacological reviews, 2015 - ASPET
… application of anticytokine therapies for other inflammatory diseases, particularly within the
… across diseases. Finally, we report on the current state of trials for newer therapeutic targets, …
… across diseases. Finally, we report on the current state of trials for newer therapeutic targets, …
[HTML][HTML] Targeting mitochondrial reactive oxygen species as novel therapy for inflammatory diseases and cancers
… and the application of mtROS-targeting drugs in the research is significant towards
development of better therapies to combat inflammatory diseases and inflammatory malignancies. …
development of better therapies to combat inflammatory diseases and inflammatory malignancies. …
Targeted delivery systems for biological therapies of inflammatory diseases
… discusses various targeting strategies for biological therapies of inflammatory diseases, with
… , recent advances in the development of targeted delivery systems for gene therapy against …
… , recent advances in the development of targeted delivery systems for gene therapy against …
Discovery and development of folic-acid-based receptor targeting for imaging and therapy of cancer and inflammatory diseases
PS Low, WA Henne… - Accounts of chemical …, 2008 - ACS Publications
… our quest for the ideal targeted therapeutic agent. This effort … After identification of an optimal
targeting ligand, effort was … on malignant cells to target folate-linked pharmaceuticals to …
targeting ligand, effort was … on malignant cells to target folate-linked pharmaceuticals to …
[HTML][HTML] Translational nano-medicines: targeted therapeutic delivery for cancer and inflammatory diseases
… use of biological therapy for inflammatory disease and discuss … repolarization strategy for
inflammatory disease with a focus … -inflammatory therapy, and macrophage-targeted delivery …
inflammatory disease with a focus … -inflammatory therapy, and macrophage-targeted delivery …
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