… Phenytoin (PHT) is a common cause of severe cutaneous adverse reactions (SCARs),
including Stevens–Johnson syndrome (SJS), toxic epidermal necrolysis (TEN) and drug reaction …

… -induced SJS/TEN in the Malay and Chinese populations [ 21 ], while the HLA-B*15:13 and
HLA-B*15:02 were also associated with phenytoin-induced SCARs in the Malay population …

… severe cutaneous adverse reactions, and certain antiseizure medication‐induced severe
cutaneous adverse reactions … medication‐induced severe cutaneous adverse reactions. Thus, …

… alternative to achieve effective therapeutic dose and to possibly avoid adverse reactions. …
from the Malay population. It would be interesting to see whether the Malay population also …

… the cases compared to 15.7% in general Malay population. While another study included a
… Severe cutaneous adverse reactions to drugs are a type of delayed hypersensitivity reaction …

… -induced severe cutaneous adverse reactions in a Malay population. Pharmacogenomics J.
2017… HLA-B alleles associated with severe cutaneous reactions to antiepileptic drugs in Han …

… /SJS in the Malay population. The association demonstrated in the Malay population is not
as … repeated courses of the drug without adverse reactions should be recruited as a separate …

… This has become apparent in the event of severe cutaneous adverse reactions (SCARs),
which can be life-threatening. In this review, four hypotheses were identified to describe how …

… Cutaneous reactions are most common manifestations seen in hypersensitivity reactions of
drugs, named cutaneous adverse drug reactions… into severe cutaneous adverse reactions (…

… Aim: Phenytoin (PHT) is a common anticonvulsant agent known for inducing severe
cutaneous adverse reactions (SCARs). HLA-B*15:02 as a risk factor of PHT-induced SCARs was …