[HTML][HTML] Systems biology in inflammatory bowel diseases: on the way to precision medicine
… We neither want nor need more meaningless data, but rather clear information about how
to approach, evaluate and treat a disorder. It is apparent that systems biology is years away …
to approach, evaluate and treat a disorder. It is apparent that systems biology is years away …
Inflammatory bowel disease meets systems biology: a multi-omics challenge and frontier
O Palmieri, T Mazza, S Castellana, A Panza… - OMICS: A Journal of …, 2016 - liebertpub.com
… The inflammatory bowel disease (IBD) is a systemic disease that is characterized by the …
Systems biology approaches for inflammatory bowel disease: Emphasis on gut microbial …
Systems biology approaches for inflammatory bowel disease: Emphasis on gut microbial …
[HTML][HTML] Systems biology approach highlights mechanistic differences between Crohn's disease and ulcerative colitis
PA Ruiz Castro, H Yepiskoposyan, S Gubian… - Scientific Reports, 2021 - nature.com
The molecular mechanisms of IBD have been the subject of intensive exploration. We,
therefore, assembled the available information into a suite of causal biological network models, …
therefore, assembled the available information into a suite of causal biological network models, …
Cell‐level systems biology model to study inflammatory bowel diseases and their treatment options
S Stübler, C Kloft, W Huisinga - CPT: Pharmacometrics & …, 2023 - Wiley Online Library
… To help understand the complex and therapeutically challenging inflammatory bowel
diseases (IBDs), we developed a systems biology model of the intestinal immune system that is …
diseases (IBDs), we developed a systems biology model of the intestinal immune system that is …
Systems biology approaches for inflammatory bowel disease: emphasis on gut microbial metabolism
… of inflammatory bowel disease (IBD) has risen considerably over the last decades, their
clinical features do not allow accurate prediction of prognosis, likelihood of disease progression, …
clinical features do not allow accurate prediction of prognosis, likelihood of disease progression, …
[HTML][HTML] Detection of molecular signatures and pathways shared in inflammatory bowel disease and colorectal cancer: a bioinformatics and systems biology approach
… between the two diseases and how the IBD might influence the development of CRC is still
not clearly understood. In the present study, we employed a systems biology approach to get …
not clearly understood. In the present study, we employed a systems biology approach to get …
Metagenomic systems biology of the human gut microbiome reveals topological shifts associated with obesity and inflammatory bowel disease
S Greenblum, PJ Turnbaugh… - Proceedings of the …, 2012 - National Acad Sciences
… Here, we introduce a metagenomic systems biology computational framework, integrating
metagenomic data with an in silico systems-level analysis of metabolic networks. Focusing on …
metagenomic data with an in silico systems-level analysis of metabolic networks. Focusing on …
IBD systems biology is here to stay
C Fiocchi, D Iliopoulos - Inflammatory bowel diseases, 2021 - academic.oup.com
… In fact, systems biology does not stand alone but in the … disorders of a neoplastic or
inflammatory nature. Armed with these notions and tools, this review considers why systems biology …
inflammatory nature. Armed with these notions and tools, this review considers why systems biology …
[HTML][HTML] Network biology approaches to achieve precision medicine in inflammatory bowel disease
JP Thomas, D Modos, T Korcsmaros… - Frontiers in …, 2021 - frontiersin.org
… Network biology, a branch of systems biology that utilises … Systems biology is an
interdisciplinary field that allows the … of systems biology, to facilitate precision medicine in IBD. …
interdisciplinary field that allows the … of systems biology, to facilitate precision medicine in IBD. …
[HTML][HTML] A systems pharmacology model for inflammatory bowel disease
V Balbas-Martinez, L Ruiz-Cerdá, I Irurzun-Arana… - PLoS …, 2018 - journals.plos.org
… in SPIDDOR R package [28], which allows translation of Boolean models (excluding
models enclosing temporal operators) to a standard Markup language in Systems Biology for …
models enclosing temporal operators) to a standard Markup language in Systems Biology for …
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