A spectroscopic study on the interaction between the anticancer drug erlotinib and human serum albumin

Z Ye, Y Ying, X Yang, Z Zheng, J Shi, Y Sun… - Journal of Inclusion …, 2014 - Springer
… The aim of the present investigation was to study the association of erlotinib with HSA using
fluorescence UV–Vis and circular dichroism (CD) spectroscopy to understand the carrier …

[HTML][HTML] Spectroscopic studies on the interaction between erlotinib hydrochloride and bovine serum albumin

F Rasoulzadeh, D Asgari, A Naseri… - DARU Journal of …, 2010 - ncbi.nlm.nih.gov
… a drug. In the present study, the mutual interaction of anticancer drug erlotinib hydrochloride
… bovine serum albumin (BSA) using fluorescence and UV/vis spectroscopy was investigated. …

[HTML][HTML] Vibrational fingerprint of erlotinib: FTIR, RS, and DFT studies

N Piergies, C Paluszkiewicz, WM Kwiatek - Journal of Spectroscopy, 2019 - hindawi.com
… this study, we provide the first Fourier-transform infrared absorption spectroscopy (FTIR) and
Raman spectroscopy (… Raman spectroscopy studies of a novel group of boron analogues of …

Erlotinib

AA Abdelgalil, HM Al-Kahtani, FI Al-Jenoobi - Profiles of Drug Substances …, 2020 - Elsevier
Erlotinib inhibited epidermal growth factor receptor (EGFR) … This study presents a
comprehensive profile of erlotinib, … methods of analysis (including spectroscopic, electrochemical, …

Identification of erlotinib adsorption pattern onto silver nanoparticles: SERS studies

N Piergies, M Oćwieja, C Paluszkiewicz… - … Spectroscopy, 2018 - Wiley Online Library
… Here, we present the first Raman spectroscopy studies of erlotinib immobilized onto silver …
These nanostructures were used for the first time as a surface-enhanced Raman spectroscopy

[HTML][HTML] … inhibitor erlotinib with a model transport protein in the presence of quercetin: A drug–protein and drugdrug interaction investigation using multi-spectroscopic …

TA Wani, MM Alanazi, NA Alsaif, AH Bakheit, S Zargar… - Molecules, 2022 - mdpi.com
… Therefore, various spectroscopic experiments were conducted in addition to in silico studies
to evaluate the interaction behavior of the BSA-ERL system in the presence and absence of …

Density functional methods study on the structures and spectral characteristics for pharmacophoric conformers, metabolites, and combined fragments of Erlotinib

YY Weng, X Sun, LX Wang, YY Liao, CJ Wang - Chemical Papers, 2022 - Springer
… According to the energetics and spectroscopic characteristics, either the Erlotinib itself or
its complexes and metabolites in conformation A or B could be distinguished in aqueous …

Probing the combination of erlotinib hydrochloride, an anticancer drug, and human serum albumin: Spectroscopic, molecular docking, and molecular dynamic …

S Shahraki, Z Razmara, HS Delarami… - …, 2023 - Wiley Online Library
Studying the interaction of drugs with important biological molecules such as proteins and …
HSA and Erlotinib hydrochloride (Erlo) has been studied using multispectroscopic, molecular …

Comparative studies on the human serum albumin binding of the clinically approved EGFR inhibitors gefitinib, erlotinib, afatinib, osimertinib and the investigational …

O Dömötör, K Pelivan, A Borics, BK Keppler… - … of Pharmaceutical and …, 2018 - Elsevier
… Therefore, we aimed to study the interaction of OSI and the experimental drug KP2187
from our group (Chart 1) with HSA and to compare the data with the three approved EGFR …

Characterizing the binding interaction between erlotinib and calf thymus DNA in vitro using multi‐spectroscopic methodologies and viscosity measurement combined …

XJ Chen, BL Wang, KL Zhou, YY Lou, SB Kou… - …, 2019 - Wiley Online Library
… The purpose of this study is to assess the interaction … -spectroscopic approaches combined
with theoretical calculation were performed in this work. It can be anticipated that this study