A large gene family in fission yeast encodes spore killers that subvert Mendel's law
… that there are at least two spore killer genes on chromosome III of CBS5557. To narrow
down the genomic regions containing the spore killer genes, we performed multiple rounds of …
down the genomic regions containing the spore killer genes, we performed multiple rounds of …
Molecular mechanisms and evolutionary consequences of spore killers in ascomycetes
S Zanders, H Johannesson - Microbiology and Molecular Biology …, 2021 - Am Soc Microbiol
… the genes of the Spok gene family underlie the Psk spore killers (49), and the relationship
between the Spok gene family … two genes of the Spok gene family, Spok1 and Spok2, as novel …
between the Spok gene family … two genes of the Spok gene family, Spok1 and Spok2, as novel …
The spore killers, fungal meiotic driver elements
… Although we currently only have two examples of spore killing gene family expansion, they
both suggest that the prevailing forces promote diversification into independent drivers, rather …
both suggest that the prevailing forces promote diversification into independent drivers, rather …
[HTML][HTML] Proliferation and dissemination of killer meiotic drive loci
… represent true spore killer gene families, or recent co-option of domestic gene families requires
… These observations lead us to hypothesize that gene family expansion of killer meiotic …
… These observations lead us to hypothesize that gene family expansion of killer meiotic …
Killer Meiotic Drive and Dynamic Evolution of the wtf Gene Family
MT Eickbush, JM Young… - Molecular Biology and …, 2019 - academic.oup.com
… of identified meiotic drive genes. Here, we analyze the evolution of the wtf gene family of
Schizosaccharomyces pombe that contains both killer meiotic drive genes and suppressors of …
Schizosaccharomyces pombe that contains both killer meiotic drive genes and suppressors of …
On the mechanistic basis of killer meiotic drive in fungi
SJ Saupe, H Johannesson - Annual Review of Microbiology, 2022 - annualreviews.org
… Spore killers are specific genetic elements in fungi that kill … The gene family was poorly
characterized, but several … of the wtf gene family act as autonomous spore-killing elements, …
characterized, but several … of the wtf gene family act as autonomous spore-killing elements, …
A natural fungal gene drive enacts killing via DNA disruption
AS Urquhart, DM Gardiner - Mbio, 2023 - Am Soc Microbiol
… spore killer protein Spok1, which has homologues throughout the fungal tree of life, acts via
DNA disruption. Spok1 is only the second spore killer … will be conserved in this gene family. …
DNA disruption. Spok1 is only the second spore killer … will be conserved in this gene family. …
Fungal ribotoxins: molecular dissection of a family of natural killers
J Lacadena, E Álvarez-García… - FEMS microbiology …, 2007 - academic.oup.com
… RNase T1 is the best known representative of a large family of ribonucleolytic proteins …
within a universally conserved sequence of the large rRNA gene, known as the sarcin–ricin loop. …
within a universally conserved sequence of the large rRNA gene, known as the sarcin–ricin loop. …
Genetic villains: killer meiotic drivers
… An imbalance of Slx and Sly copy numbers in hybrids or knockdown of either gene family …
the phenotypes of mutants in which the gamete (or spore)-specific component is absent. In …
the phenotypes of mutants in which the gamete (or spore)-specific component is absent. In …
A family of killers
M De Carvalho, SE Zanders - Elife, 2019 - elifesciences.org
… two new Spok genes (Spok3 and Spok4) that are both spore killers. … gene family underlies
the Psks. The combination of Spok genes at different chromosomal locations defines the spore …
the Psks. The combination of Spok genes at different chromosomal locations defines the spore …