Epigenetic small molecule modulators of histone and DNA methylation

AT Hauser, D Robaa, M Jung - Current Opinion in Chemical Biology, 2018 - Elsevier
… on small molecule modulators of DNA and histone methylation. … DNA methylation, histone
modifications and noncoding RNAs [4]. DNA methylation is deposited and maintained by DNA-…

DNA methylation and differentiation: silencing, upregulation and modulation of gene expression

M Ehrlich, M Lacey - Epigenomics, 2013 - Future Medicine
… Differentiation-related DNA methylation is receiving … methylation in gene bodies is more
frequent than in promoters. We review new insights into the functionality of DNA methylation

[HTML][HTML] Epigenetic modulation of DNA methylation by nutrition and its mechanisms in animals

N Zhang - Animal nutrition, 2015 - Elsevier
DNA methylation process contributed the most significance of the … modulation of DNA
methylation were reviewed here. … DNA methylation; second, provision of cofactors modulating the …

[PDF][PDF] Role of DNA methylation in modulating transcription factor occupancy

MT Maurano, H Wang, S John, A Shafer, T Canfield… - Cell reports, 2015 - cell.com
… of DNA methylation in the active modulation of TF binding, we quantified the effect of DNA
… of CTCF, an abundant TF with known methylation sensitivity that is capable of autonomous …

Biological and biochemical modulation of DNA methylation

R Lo, R Weksberg - Epigenomics, 2014 - Future Medicine
… This review will focus on DNA methylation and DNA methyltransferases with … modulating
DNA methylation. Other physiological and biochemical factors that can modify DNA methylation

[HTML][HTML] DNA methylation: Precise modulation of chromatin structure and dynamics

S Li, Y Peng, AR Panchenko - Current opinion in structural biology, 2022 - Elsevier
DNA methylation is also involved in the modulation of three-dimensional chromatin structure
[46]. Indeed, the DNA methylation loss resulting from mutations in DNA-… DNA methylation

Targeting DNA methylation

JPJ Issa, HM Kantarjian - Clinical Cancer Research, 2009 - AACR
… of DNA methylation. As soon as embryogenesis begins, a massive decrease in DNA methylation
… and gene mutation confirmed that epigenetic modulation precedes clonal elimination in …

Modulation of DNA methylation by a sesquiterpene lactone parthenolide

Z Liu, S Liu, Z Xie, RE Pavlovicz, J Wu, P Chen… - … of Pharmacology and …, 2009 - ASPET
Modulation of DNA methylation with DNA methylation … Currently, effective DNA methylation
inhibitors are mainly limited … In this article, we report that parthenolide 1) inhibits DNA

An epigenomic roadmap to induced pluripotency reveals DNA methylation as a reprogramming modulator

DS Lee, JY Shin, PD Tonge, MC Puri, S Lee… - Nature …, 2014 - nature.com
… We find that DNA methylation gain during … low methylation and strong engagement of
histone marks, whereas genes with CpG-poor promoters are safeguarded by methylation. Such …

Dietary fat and obesity as modulators of breast cancer risk: Focus on DNA methylation

MG Donovan, SN Wren, M Cenker… - British Journal of …, 2020 - Wiley Online Library
… review is to highlight studies documenting modulating effects of dietary fatty acids (… DNA
CpG methylation. We focus our review on DNA methylation given that detecting CpG methylation