DNA methylation: roles in mammalian development

ZD Smith, A Meissner - Nature Reviews Genetics, 2013 - nature.com
… two developmental periods, primordial germ cell (PGC) specification and the early embryo,
in which DNA methylation … principles of DNA methylation in mammalian development and set …

The diverse roles of DNA methylation in mammalian development and disease

MVC Greenberg, D Bourc'his - Nature reviews Molecular cell biology, 2019 - nature.com
… of DNA methylation and its establishment, maintenance and erasure during mammalian
development. … gained into the patterning of DNA methylation during development. Finally, we …

[HTML][HTML] DNA methylation reprogramming during mammalian development

Y Zeng, T Chen - Genes, 2019 - mdpi.com
… , are usually devoid of methylation [2]. DNA methylation is essential for mammalian development
and is involved in … Aberrant DNA methylation patterns and mutations of genes encoding …

Notes on the role of dynamic DNA methylation in mammalian development

TH Bestor, JR Edwards… - Proceedings of the …, 2015 - National Acad Sciences
… bear either methylated or unmethylated genomes argues against a major role for DNA
methylation in mammalian development, as do the low levels of promoter methylation and lack of …

Functions of DNA methylation and hydroxymethylation in mammalian development

S Guibert, M Weber - Current topics in developmental biology, 2013 - Elsevier
DNA methylation plays multiple roles during development and serves to establish long-term
gene … discoveries on the role of cytosine epigenetic marks during mammalian development. …

DNA methylation in mammalian development and disease

W Dean, D Lucifero, F Santos - Birth Defects Research Part C …, 2005 - Wiley Online Library
… Establishing the importance of DNA methylation and its regulation to ensure normal
mammalian development naturally forces us to consider the possibilities and repercussions of its …

Expression of various genes is controlled by DNA methylation during mammalian development

M Ehrlich - Journal of cellular biochemistry, 2003 - Wiley Online Library
DNA methylation controlling their expression during normal mammalian development and
a … For descriptions of some of the evidence for DNA methylation-controlled expression of X-…

The role of DNA methylation in mammalian development

CE Senner - Reproductive biomedicine online, 2011 - Elsevier
… This review considers the dynamic patterns of DNA methylation throughout gametogenesis,
preimplantation development and early lineage commitment, along with recent insights into …

DNA methylation in animal development

RR Meehan - Seminars in cell & developmental biology, 2003 - Elsevier
… is essential for normal vertebrate development but has distinct regulatory roles in non-mammalian
and mammalian vertebrates. In mammals, DNA methylation has an additional role in …

DNA methylation, genomic imprinting, and mammalian development

E Li, C Beard, AC Forster, TH Bestor… - Cold Spring Harbor …, 1993 - symposium.cshlp.org
… of DNA modification in mammalian gene control and develop… importance of DNA methylation
in vertebrate development … of CpG methylation due to a defect in the DNA MTase gene. ES …