Changes in DNA methylation in neoplasia: pathophysiology and therapeutic implications

V Santini, HM Kantarjian, JP Issa - Annals of internal medicine, 2001 - acpjournals.org
Methylation of DNA is a biochemical modification that can … of abnormalities in DNA methylation
may therefore restore the … rationale for targeting aberrant methylation in cancer therapy …

[HTML][HTML] Tobacco smoking leads to extensive genome-wide changes in DNA methylation

S Zeilinger, B Kühnel, N Klopp, H Baurecht… - PloS one, 2013 - journals.plos.org
change of 6.1. Upon smoking cessation, the expression of this gene fell extensively, but
changes … which corresponds to the progress of DNA methylation changes we were able to detect …

DNA methylation and healthy human aging

MJ Jones, SJ Goodman, MS Kobor - Aging cell, 2015 - Wiley Online Library
Changes in DNA methylation occur throughout the lifetime, beginning at conception. Early
studies assessing levels of DNA methylation … that gradual change in DNA methylation occurs …

Changes in DNA methylation patterns in subjects exposed to low-dose benzene

V Bollati, A Baccarelli, L Hou, M Bonzini, S Fustinoni… - Cancer research, 2007 - AACR
… exposure on DNA methylation using peripheral blood DNA from … to evaluate (a) DNA
methylation changes in AluI and long … of genome-wide methylation, (b) promoter methylation of …

Global changes in DNA methylation and hydroxymethylation in Alzheimer's disease human brain

N Coppieters, BV Dieriks, C Lill, RLM Faull… - Neurobiology of …, 2014 - Elsevier
… Our results indicate that levels of 5mC and 5hmC positively correlate with Aβ, NFTs, and
ubiquitin loads found in MTG suggesting that increases in DNA methylation and …

Impact of aging on DNA methylation

B Richardson - Ageing research reviews, 2003 - Elsevier
DNA methylation, the changes in DNA methylation can also impact on aging. This review
summarizes current evidence for changes in the methylation … altered DNA methylation patterns. …

[PDF][PDF] Tracing dynamic changes of DNA methylation at single-cell resolution

Y Stelzer, CS Shivalila, F Soldner, S Markoulaki… - Cell, 2015 - cell.com
… to capture dynamic DNA methylation changes in distal non-coding regulatory regions. An
attractive aspect of RGM is its utility to visualize DNA methylation changes in development and …

Extensive changes in DNA methylation are associated with expression of mutant huntingtin

CW Ng, F Yildirim, YS Yap, S Dalin… - Proceedings of the …, 2013 - National Acad Sciences
… been shown to undergo methylation changes in response to … change in methylation, we
identify AP-1 and SOX2 as transcriptional regulators associated with DNA methylation changes, …

Global changes in DNA methylation in Alzheimer's disease peripheral blood mononuclear cells

A Di Francesco, B Arosio, A Falconi… - Brain, behavior, and …, 2015 - Elsevier
Changes in epigenetic marks may help explain the late … DNA methylation by luminometric
methylation assay, a quantitative measurement of genome-wide DNA methylation, on DNA

Temporal and regional changes in DNA methylation in the embryonic, extraembryonic and germ cell lineages during mouse embryo development

M Monk, M Boubelik, S Lehnert - Development, 1987 - journals.biologists.com
… subsequent analysis of overall genomic DNA methylation by end-labelling. The end-label
technique allows comparisons of overall genomic DNA methylation in the DNA of as few as …