From stress to inflammation and major depressive disorder: a social signal transduction theory of depression.
GM Slavich, MR Irwin - Psychological bulletin, 2014 - psycnet.apa.org
Major life stressors, especially those involving interpersonal stress and social rejection, are
among the strongest proximal risk factors for depression. In this review, we propose a …
among the strongest proximal risk factors for depression. In this review, we propose a …
Stress, sex hormones, inflammation, and major depressive disorder: Extending Social Signal Transduction Theory of Depression to account for sex differences in …
GM Slavich, J Sacher - Psychopharmacology, 2019 - Springer
Abstract Social Signal Transduction Theory of Depression is a biologically plausible, multi-
level theory that describes neural, physiologic, molecular, and genomic mechanisms that …
level theory that describes neural, physiologic, molecular, and genomic mechanisms that …
Current understanding of the bi-directional relationship of major depression with inflammation
B Messay, A Lim, AL Marsland - Biology of mood & anxiety disorders, 2012 - Springer
Consistent evidence links major depression and its affective components to negative health
outcomes. Although the pathways of these effects are likely complex and multifactorial …
outcomes. Although the pathways of these effects are likely complex and multifactorial …
The role of inflammation in core features of depression: Insights from paradigms using exogenously-induced inflammation
LN Dooley, KR Kuhlman, TF Robles… - Neuroscience & …, 2018 - Elsevier
A wealth of evidence has implicated inflammation in the development of depression. Yet, the
heterogeneous nature of depression has impeded efforts to understand, prevent, and treat …
heterogeneous nature of depression has impeded efforts to understand, prevent, and treat …
Cytokines sing the blues: inflammation and the pathogenesis of depression
CL Raison, L Capuron, AH Miller - Trends in immunology, 2006 - cell.com
Increasing amounts of data suggest that inflammatory responses have an important role in
the pathophysiology of depression. Depressed patients have been found to have higher …
the pathophysiology of depression. Depressed patients have been found to have higher …
Cascading effects of stressors and inflammatory immune system activation: implications for major depressive disorder
H Anisman - Journal of Psychiatry and Neuroscience, 2009 - jpn.ca
Activation of the inflammatory immune system provokes numerous neuroendocrine and
neurotransmitter changes, many of which are similar to those provoked by physical or …
neurotransmitter changes, many of which are similar to those provoked by physical or …
Stress-induced microglia activation and monocyte trafficking to the brain underlie the development of anxiety and depression
Psychosocial stress is capable of causing immune dysregulation and increased
neuroinflammatory signaling by repeated activation of the neuroendocrine and autonomic …
neuroinflammatory signaling by repeated activation of the neuroendocrine and autonomic …
The interplay between stress, inflammation, and emotional attention: relevance for depression
V Maydych - Frontiers in neuroscience, 2019 - frontiersin.org
Depression is among the most significant public mental health issues. A growing body of
research implicates inflammation in the etiology and pathophysiology of depression. Yet, the …
research implicates inflammation in the etiology and pathophysiology of depression. Yet, the …
The role of inflammatory mediators in the biology of major depression: central nervous system cytokines modulate the biological substrate of depressive symptoms …
Depression represents a major public health problem. It is estimated that 13–20% of the
population has some depressive symptoms at any given time and about 5% of the …
population has some depressive symptoms at any given time and about 5% of the …
Toward an anti-inflammatory strategy for depression
S Hayley - Frontiers in behavioral neuroscience, 2011 - frontiersin.org
It has become clear that the inflammatory immune system is altered during the course of
clinical depression. In particular, studies on human patients have found depression to be …
clinical depression. In particular, studies on human patients have found depression to be …