NF-ATc1 is a member of a family of genes that encodes the cytoplasmic component of the
nuclear factor of activated T cells (NF-AT). In activated T cells, nuclear NF-AT binds to the …

The NF-AT family of transcription factors activates early immune response genes such as
cytokines. In the adult, NF-ATc is expressed exclusively in the lymphoid system and is …

NF-ATp is a member of a family of genes that encodes the cytoplasmic component of the
nuclear factor of activated T cells (NF-AT). In this study, we show that mice with a null …

The family of genuine NF-AT transcription factors consists of four members (NF-AT1 [or NF-
ATp], NF-AT2 [or NF-ATc], NF-AT3 and NF-AT4 [or NF-ATx]) which are characterized by a …

The activation of cytokine genes in response to antigenie stimulation of T cells is mediated
by NF-AT proteins. Previous studies have identified two NF-AT proteins, NF-ATp and NF …

The lymphoid-specific transcription complex, NF-AT, is involved in early gene activation in T
cells and is assembled from a pre-existing, T cell restricted cytoplasmic factor and an …

The transcription factor NF-ATc that controls gene expression in T lymphocytes and
embryonic cardiac cells is expressed in three prominent isoforms. This is due to alternative …

The nuclear factor of activated T cells (NFAT) regulates cytokine gene expression in T cells
through cis-acting elements located in the promoters of cytokine genes. Here, we report the …

Transcription factors of the nuclear factor of activated T cells (NFAT) family are thought to
regulate the expression of a variety of inducible genes such as interleukin-2 (IL-2), IL-4, and …

The human tumor necrosis factor alpha (TNF-α) gene is one of the earliest genes expressed
upon the activation of a T or B cell through its antigen receptor. Previous experiments have …