FGF5 stimulates expansion of connective tissue fibroblasts and inhibits skeletal muscle development in the limb

KL Clase, PJ Mitchell, PJ Ward… - … dynamics: an official …, 2000 - Wiley Online Library
FGF5 is expressed in the mesenchyme and skeletal muscle of developing and adult mouse
limbs. However, the function of FGF5 during development of the limb and limb musculature …

Role of FGFs in skeletal muscle and limb development

BB Olwin, K Arthur, K Hannon, P Hein… - Molecular …, 1994 - Wiley Online Library
Fibroblast growth factors (FGFs) are a family of nine proteins that bind to three distinct types
of cell surface molecules:(i) FGF receptor tyrosine kinases (FGFR1 through FGFR4);(ii) a …

Murine FGF-4 gene expression is spatially restricted within embryonic skeletal muscle and other tissues

BJ Drucker, M Goldfarb - Mechanisms of development, 1993 - Elsevier
Fibroblast growth factors are believed to play many distinct roles in vertebrate development,
owing to their ability to stimulate cell growth, prevent cell death, determine cell fate, and …

[PDF][PDF] Identification of cis-elements regulating expression of Fgf10 during limb development

H Sasaki, T Yamaoka, H Ohuchi, A Yasue… - International Journal of …, 2002 - academia.edu
ABSTRACT Fibroblast growth factor 10 (FGF10) is known to be expressed in limb
mesenchymal cells and to function as a mesenchymal signaling factor involved in epithelial …

Identification of a fibroblast growth factor 6 (FGF6) gene in a non-mammalian vertebrate: continuous expression of FGF6 accompanies muscle fiber hyperplasia

PY Rescan - Biochimica et Biophysica Acta (BBA)-Gene Structure …, 1998 - Elsevier
FGF6, a member of the fibroblast growth factor (FGF) family, is specifically expressed in
developing skeletal muscle and may participate in muscle maintenance and regeneration …

[HTML][HTML] Fgf8 transcripts are located in tendons during embryonic chick limb development

F Edom-Vovard, MA Bonnin, D Duprez - Mechanisms of development, 2001 - Elsevier
Fibroblast growth factor 8 (Fgf8) is a secreted growth factor involved in the initiation,
outgrowth and patterning of vertebrate limbs (Genes Dev. 12 (1998) 1571). In this paper, we …

Misexpression of Fgf-4 in the chick limb inhibits myogenesis by down-regulating Frek expression

F Edom-Vovard, MA Bonnin, D Duprez - Developmental biology, 2001 - Elsevier
Skeletal muscle development involves an initial period of myoblast replication followed by a
phase in which some myoblasts continue to proliferate while others undergo terminal …

Expression of the Fgf6 gene is restricted to developing skeletal muscle in the mouse embryo

O Delapeyrière, V Ollendorff, J Planche… - …, 1993 - journals.biologists.com
Fgf6, a member of the Fibroblast Growth Factor (FGF) family, is developmentally regulated
and its expression is highly restricted in the adult. To gain further insight into the role of Fgf6 …

Involvement of FGF-8 in initiation, outgrowth and patterning of the vertebrate limb

A Vogel, C Rodriguez, JC Izpisúa-Belmonte - Development, 1996 - journals.biologists.com
ABSTRACT Fibroblast Growth Factors (FGFs) are signaling molecules that are important in
patterning and growth control during vertebrate limb development. Beads soaked in FGF-1 …

Differentially expressed fibroblast growth factors regulate skeletal muscle development through autocrine and paracrine mechanisms.

K Hannon, AJ Kudla, MJ McAvoy, KL Clase… - The Journal of cell …, 1996 - rupress.org
Several FGF family members are expressed in skeletal muscle; however, the roles of these
factors in skeletal muscle development are unclear. We examined the RNA expression …