Carbonic anhydrase IX expression predicts outcome of interleukin 2 therapy for renal cancer

M Atkins, M Regan, D McDermott, J Mier… - Clinical cancer …, 2005 - AACR
Purpose: Renal cancer response to interleukin 2 (IL-2) therapy and patient survival has
been correlated with tumor histology and carbonic anhydrase IX (CAIX) expression. In an …

Quantification of carbonic anhydrase IX expression in serum and tissue of renal cell carcinoma patients using enzyme-linked immunosorbent assay: prognostic and …

GX Zhou, J Ireland, P Rayman, J Finke, M Zhou - Urology, 2010 - Elsevier
OBJECTIVES: To validate enzyme-linked immunosorbent assay (ELISA) as an accurate and
objective method to measure carbonic anhydrase IX (CAIX) expression in RCC tissue …

Carbonic anhydrase IX is not an independent predictor of outcome for patients with clear cell renal cell carcinoma

BC Leibovich, Y Sheinin, CM Lohse… - Journal of clinical …, 2007 - ascopubs.org
Purpose Expression of carbonic anhydrase IX (CAIX) has been reported to be an
independent predictor of outcome and is being investigated as a therapeutic target for …

Carbonic anhydrase IX is an independent predictor of survival in advanced renal clear cell carcinoma: implications for prognosis and therapy

MHT Bui, D Seligson, K Han, AJ Pantuck, FJ Dorey… - Clinical cancer …, 2003 - AACR
Purpose: Metastatic renal cell carcinoma (RCC) has a poor prognosis and an unpredictable
course. To date, there are no molecular markers which can reliably predict RCC outcome …

Carbonic anhydrase IX in renal cell carcinoma: implications for prognosis, diagnosis, and therapy

AB Stillebroer, PFA Mulders, OC Boerman, WJG Oyen… - European urology, 2010 - Elsevier
CONTEXT: The clinical management of patients with renal cell carcinoma (RCC) remains
difficult, and the development of new diagnostic, prognostic, and therapeutic tools is still …

Carbonic anhydrase IX expression in clear cell renal cell carcinoma: an immunohistochemical study comparing 2 antibodies

HA Al-Ahmadie, D Alden, LX Qin, S Olgac… - The American journal …, 2008 - journals.lww.com
Carbonic anhydrase IX (CAIX)—a protein maintaining intracellular and extracellular pH—
reportedly also influences regulation of cell proliferation, oncogenesis, and tumor …

Carbonic anhydrase IX expression in renal neoplasms: correlation with tumor type and grade

EM Genega, M Ghebremichael… - American journal of …, 2010 - academic.oup.com
Carbonic anhydrase IX (CAIX), a hypoxia-induced protein, is expressed in some renal
tumors. We evaluated its immunohistochemical expression in 317 primary and 42 metastatic …

Prognostic impact of carbonic anhydrase IX expression in human renal cell carcinoma

J Sandlund, E Oosterwijk, K Grankvist… - BJU …, 2007 - Wiley Online Library
OBJECTIVE To evaluate the prognostic information of carbonic anhydrase (CA) IX
expression in patients with renal cell carcinoma (RCC), as increased expression of CA IX is …

Carbonic anhydrase IX in renal cell carcinoma, implications for disease management

J Courcier, A de la Taille, M Nourieh… - International journal of …, 2020 - mdpi.com
Carbonic Anhydrase IX (CAIX) is a well-described enzyme in renal cell carcinoma, with its
expression being regulated by the hypoxia-inducible factor 1 alpha, it is known for interfering …

Carbonic anhydrase IX in bladder cancer: a diagnostic, prognostic, and therapeutic molecular marker

T Klatte, DB Seligson, JY Rao, H Yu… - … Journal of the …, 2009 - Wiley Online Library
BACKGROUND: The objective of this study was to evaluate the role of carbonic anhydrase
IX (CAIX) in urothelial carcinoma of the bladder. METHODS: A tissue microarray was …