Anti‐N and anti‐Doa immunoglobulin G alloantibody–mediated delayed hemolytic transfusion reaction with hyperhemolysis in sickle cell disease treated with …

A Unnikrishnan, JPR Pelletier, S Bari, M Zumberg… - …, 2019 - Wiley Online Library
BACKGROUND Delayed hemolytic transfusion reaction (DHTR) with hyperhemolysis is a
potentially fatal complication resulting from alloimmunization that can cause severe …

Challenges in the treatment and prevention of delayed hemolytic transfusion reactions with hyperhemolysis in sickle cell disease patients

CL Dean, CL Maier, S Chonat, A Chang… - …, 2019 - Wiley Online Library
BACKGROUND Delayed hemolytic transfusion reactions (DHTRs) are serious complications
of RBC transfusion that can occur in previously alloimmunized patients. Patients who require …

Life‐threatening delayed hyperhemolytic transfusion reaction in a patient with sickle cell disease: effective treatment with eculizumab followed by rituximab

M Boonyasampant, IC Weitz, B Kay… - …, 2015 - Wiley Online Library
BACKGROUND Hyperhemolysis in sickle cell disease is a rare and potentially life‐
threatening complication of transfusion. STUDY DESIGN AND METHODS In this article we …

Rituximab for prevention of delayed hemolytic transfusion reaction in sickle cell disease

F Noizat-Pirenne, D Bachir, P Chadebech… - …, 2007 - haematologica.org
Delayed hemolytic transfusion reaction (DHTR), a life-threatening transfusion complication
in sickle cell disease (SCD), is characterized by a marked hemoglobin drop with destruction …

Alloimmunization in patients with sickle cell disease and underrecognition of accompanying delayed hemolytic transfusion reactions

S Coleman, CM Westhoff, DF Friedman, ST Chou - Transfusion, 2019 - Wiley Online Library
BACKGROUND Patients with sickle cell disease (SCD) often require red blood cell (RBC)
transfusions but alloimmunization remains a significant complication. Alloantibodies can …

The use of rituximab to prevent severe delayed haemolytic transfusion reaction in immunized patients with sickle cell disease

F Noizat‐Pirenne, A Habibi… - Vox …, 2015 - Wiley Online Library
Background Delayed haemolytic transfusion reaction (DHTR) is mainly caused by an
immune response to transfused red blood cells (RBC s). Immunized patients have a high …

Clinical presentation of delayed hemolytic transfusion reactions and hyperhemolysis in sickle cell disease

RM Fasano, MJ Miller, S Chonat, SR Stowell - Transfusion Clinique et …, 2019 - Elsevier
Red blood cell (RBC) transfusion therapy is a key component in the comprehensive
management of patients with sickle cell disease (SCD). Consequently, most adult SCD …

Successful outcome of hyperhemolysis in sickle cell disease following multiple lines of treatment: the role of complement inhibition

E Vlachaki, E Gavriilaki, K Kafantari, D Adamidou… - …, 2018 - Taylor & Francis
Delayed hemolytic transfusion reaction (DHTR) is a life-threatening complication in patients
with sickle cell disease, characterized by difficulties in diagnosis and management. Certain …

[HTML][HTML] Anti-C5 antibody treatment for delayed hemolytic transfusion reactions in sickle cell disease

A Floch, A Morel, F Zanchetta-Balint… - …, 2020 - ncbi.nlm.nih.gov
Delayed hemolytic transfusion reaction (DHTR) is an unpredictable severe complication of
transfusion in patients with sickle cell disease (SCD). It presents clinically as a vaso …

[HTML][HTML] Hemolytic transfusion reactions in sickle cell disease: underappreciated and potentially fatal

SL Thein, F Pirenne, RM Fasano, A Habibi… - …, 2020 - ncbi.nlm.nih.gov
Patients with sickle cell disease (SCD) often receive red blood cell (RBC) transfusion
support for the prevention and management of many acute and chronic disease …