Allergen immunotherapy is allergen‐specific, allergen dose‐and time‐dependent and is
associated with long‐term clinical and immunological tolerance that persists for years after …

As the frequency of allergic disorders has increased in recent decades, concerns have been
focused on how to develop preventive approaches and implement novel treatment …

Long-term efficacy that occurs with allergen immunotherapy of proven value is associated
with decreases in IgE-dependent activation of mast cells and tissue eosinophilia. This …

Allergen immunotherapy is effective in patients with IgE-dependent allergic rhinitis and
asthma. When immunotherapy is given continuously for 3 years, there is persistent clinical …

The molecular and cellular mechanisms of allergen‐specific immunotherapy (SIT) have
recently been investigated. It appears that, similar to a normal immune response to allergen …

The two biggest success stories in allergy treatment are topical glucocorticosteroids and
allergen immunotherapy (AIT). Glucocorticosteroids, the principal pharmaceuticals of allergy …

Successful allergen-specific immunotherapy (AIT) is associated with a marked decrease in
symptoms on allergen exposure, a reduced requirement for 'rescue'anti-allergic drugs and …

Allergen-specific immunotherapy (SIT) is the only available curative treatment of allergic
diseases. Recent evidence provided a plausible explanation to its multiple mechanisms …

Clinical and immunologic tolerance are hallmarks of successful allergen immunotherapy
(AIT). Clinical benefits such as reduced symptoms, pharmacotherapy intake and …

Allergic individuals respond to an environmental allergen encounter by producing T-cell
cytokines, predominantly IL-4 and IL-5, which in turn drive the production of allergen-specific …