A sentinel platform to evaluate influenza vaccine effectiveness and new variant circulation, Canada 2010–2011 season
Abstract Background. During the 2010–2011 winter, a large number of outbreaks due to
influenza A/H3N2 at long-term care facilities, including higher-than-expected attack rates …
influenza A/H3N2 at long-term care facilities, including higher-than-expected attack rates …
Estimates of influenza vaccine effectiveness for 2007–2008 from Canada's sentinel surveillance system: cross-protection against major and minor variants
Objectives. To estimate influenza vaccine effectiveness (VE) for the 2007–2008 season and
assess the sentinel surveillance system in Canada for monitoring virus evolution and impact …
assess the sentinel surveillance system in Canada for monitoring virus evolution and impact …
Influenza vaccine effectiveness by A (H3N2) phylogenetic subcluster and prior vaccination history: 2016–2017 and 2017–2018 epidemics in Canada
DM Skowronski, S Leir, S Sabaiduc… - The Journal of …, 2022 - academic.oup.com
Abstract Background The influenza A (H3N2) vaccine was updated from clade 3C. 3a in
2015–2016 to 3C. 2a for 2016–2017 and 2017–2018. Circulating 3C. 2a viruses showed …
2015–2016 to 3C. 2a for 2016–2017 and 2017–2018. Circulating 3C. 2a viruses showed …
A perfect storm: impact of genomic variation and serial vaccination on low influenza vaccine effectiveness during the 2014–2015 season
DM Skowronski, C Chambers… - Clinical Infectious …, 2016 - academic.oup.com
Abstract Background. The 2014–2015 influenza season was distinguished by an epidemic
of antigenically-drifted A (H3N2) viruses and vaccine components identical to 2013–2014 …
of antigenically-drifted A (H3N2) viruses and vaccine components identical to 2013–2014 …
Poor immunogenicity, not vaccine strain egg adaptation, may explain the low H3N2 influenza vaccine effectiveness in 2012–2013
S Cobey, S Gouma, K Parkhouse… - Clinical Infectious …, 2018 - academic.oup.com
Background Influenza vaccination aims to prevent infection by influenza virus and reduce
associated morbidity and mortality; however, vaccine effectiveness (VE) can be modest …
associated morbidity and mortality; however, vaccine effectiveness (VE) can be modest …
Integrated sentinel surveillance linking genetic, antigenic, and epidemiologic monitoring of influenza vaccine-virus relatedness and effectiveness during the 2013 …
DM Skowronski, C Chambers… - The Journal of …, 2015 - academic.oup.com
Abstract Background. Canada's Sentinel Physician Surveillance Network links genetic,
antigenic, and vaccine effectiveness (VE) measures in an integrated platform of influenza …
antigenic, and vaccine effectiveness (VE) measures in an integrated platform of influenza …
Interim estimates of 2014/15 vaccine effectiveness against influenza A (H3N2) from Canada's Sentinel Physician Surveillance Network, January 2015
DM Skowronski, C Chambers, S Sabaiduc… - …, 2015 - eurosurveillance.org
The 2014/15 influenza season to date in Canada has been characterised by predominant
influenza A (H3N2) activity. Canada's Sentinel Physician Surveillance Network (SPSN) …
influenza A (H3N2) activity. Canada's Sentinel Physician Surveillance Network (SPSN) …
Low 2012–13 influenza vaccine effectiveness associated with mutation in the egg-adapted H3N2 vaccine strain not antigenic drift in circulating viruses
Background Influenza vaccine effectiveness (VE) is generally interpreted in the context of
vaccine match/mismatch to circulating strains with evolutionary drift in the latter invoked to …
vaccine match/mismatch to circulating strains with evolutionary drift in the latter invoked to …
Component-specific effectiveness of trivalent influenza vaccine as monitored through a sentinel surveillance network in Canada, 2006–2007
DM Skowronski, G De Serres… - The Journal of …, 2009 - academic.oup.com
Background. Trivalent inactivated influenza vaccine (TIV) is reformulated annually to contain
representative strains of 2 influenza A subtypes (H1N1 and H3N2) and 1 B lineage …
representative strains of 2 influenza A subtypes (H1N1 and H3N2) and 1 B lineage …
Interim estimates of influenza vaccine effectiveness in 2012/13 from Canada's sentinel surveillance network, January 2013
The 2012/13 influenza season in Canada has been characterised to date by early and
moderately severe activity, dominated (90%) by the A (H3N2) subtype. Vaccine …
moderately severe activity, dominated (90%) by the A (H3N2) subtype. Vaccine …