A diacylglycerol lipase-CB2 cannabinoid pathway regulates adult subventricular zone neurogenesis in an age-dependent manner

MB Goncalves, P Suetterlin, P Yip… - Molecular and Cellular …, 2008 - Elsevier
The subventricular zone (SVZ) is a major site of neurogenesis in the adult. We now show
that ependymal and proliferating cells in the adult mouse SVZ express diacylglycerol lipases …

Endocannabinoids regulate the migration of subventricular zone-derived neuroblasts in the postnatal brain

MJ Oudin, S Gajendra, G Williams… - Journal of …, 2011 - Soc Neuroscience
In the adult brain, neural stem cells proliferate within the subventricular zone before
differentiating into migratory neuroblasts that travel along the rostral migratory stream (RMS) …

The role of cannabinoids in adult neurogenesis

JA Prenderville, ÁM Kelly… - British journal of …, 2015 - Wiley Online Library
The processes underpinning post‐developmental neurogenesis in the mammalian brain
continue to be defined. Such processes involve the proliferation of neural stem cells and …

The endocannabinoid system promotes astroglial differentiation by acting on neural progenitor cells

T Aguado, J Palazuelos, K Monory, N Stella… - Journal of …, 2006 - Soc Neuroscience
Endocannabinoids exert an important neuromodulatory role via presynaptic cannabinoid
CB1 receptors and may also participate in the control of neural cell death and survival. The …

CB1 cannabinoid receptors increase neuronal precursor proliferation through AKT/glycogen synthase kinase-3β/β-catenin signaling

S Trazzi, M Steger, VM Mitrugno, R Bartesaghi… - Journal of Biological …, 2010 - ASBMB
The endocannabinoid system is involved in the regulation of many physiological effects in
the central and peripheral nervous system. Recent findings have demonstrated the …

Endocannabinoid system and adult neurogenesis: a focused review

S Oddi, L Scipioni, M Maccarrone - Current opinion in pharmacology, 2020 - Elsevier
Highlights•The endocannabinoid system is involved in all aspects of the biology of neural
stem cells.•Selective CB 1 and CB 2 agonism produces pro-neurogenic effects in different …

Activation of type 1 cannabinoid receptor (CB1R) promotes neurogenesis in murine subventricular zone cell cultures

S Xapelli, F Agasse, L Sardà-Arroyo, L Bernardino… - PloS one, 2013 - journals.plos.org
The endocannabinoid system has been implicated in the modulation of adult neurogenesis.
Here, we describe the effect of type 1 cannabinoid receptor (CB1R) activation on self …

Interaction between cannabinoid type 1 and type 2 receptors in the modulation of subventricular zone and dentate gyrus neurogenesis

RS Rodrigues, FF Ribeiro, F Ferreira, SH Vaz… - Frontiers in …, 2017 - frontiersin.org
Neurogenesis in the adult mammalian brain occurs mainly in two neurogenic niches, the
subventricular zone (SVZ) and the subgranular zone (SGZ) of the dentate gyrus (DG) …

Nerve growth factor scales endocannabinoid signaling by regulating monoacylglycerol lipase turnover in developing cholinergic neurons

E Keimpema, G Tortoriello, A Alpár… - Proceedings of the …, 2013 - National Acad Sciences
Endocannabinoid, particularly 2-arachidonoyl glycerol (2-AG), signaling has recently
emerged as a molecular determinant of neuronal migration and synapse formation during …

Brain-derived neurotrophic factor (BDNF) role in cannabinoid-mediated neurogenesis

FF Ferreira, FF Ribeiro, RS Rodrigues… - Frontiers in cellular …, 2018 - frontiersin.org
The adult mammalian brain can produce new neurons in a process called adult
neurogenesis, which occurs mainly in the subventricular zone (SVZ) and in the hippocampal …