Many metabolic pathways in microbial hosts have been created, modified and engineered to
produce useful molecules. The titer and yield of a final compound is often limited by the …

Quantification and regulation of pathway metabolites is crucial for optimization of microbial
production bioprocesses. Genetically encoded biosensors provide the means to couple …

Microbes can convert inexpensive renewable substrates to valuable metabolites by their
natural metabolic pathways. To maximize the productivity, the pathways yet require further …

Highlights•Various genetically encoded biosensors in microorganisms are
described.•Recent progress in biosensor in the context of metabolic engineering is …

Biosensors have been widely used as cost-effective, rapid, in situ, and real-time analytical
tools for monitoring environments. The development of synthetic biology has enabled …

Whole-cell biosensors are a good alternative to enzyme-based biosensors since they offer
the benefits of low cost and improved stability. In recent years, live cells have been …

In vivo biosensors can recognize and respond to specific cellular stimuli. In recent years,
biosensors have been increasingly used in metabolic engineering and synthetic biology …

Synthetic biology has progressed to the point where genes that encode whole metabolic
pathways and even genomes can be manufactured and brought to life. This impressive …

Cells are filled with biosensors, molecular systems that measure the state of the cell and
respond by regulating host processes. In much the same way that an engineer would …

A microbial biosensor is an analytical device with a biologically integrated transducer that
generates a measurable signal indicating the analyte concentration. This method is ideally …