Background & Aims Mesenchymal stem cell (MSC) transplantation was shown to be
effective for the treatment of liver fibrosis, but the mechanisms of action are not yet fully …

Background Liver fibrosis is a key phase that will progress to further injuries such as liver
cirrhosis or carcinoma. This study aimed to investigate whether transplantation of bone …

We describe a novel therapeutic approach for cirrhosis using mesenchymal stem cells
(MSCs) and colony-stimulating factor-1-induced bone marrow-derived macrophages (id …

AIM: To compare the influence of different transplant sites in bone marrow mesenchymal
stem cell (MSC)-based therapy for liver fibrosis. METHODS: MSCs isolated from Sprague …

AIM: Recent reports have shown the capacity of mesenchymal stem cells (MSCs) to
differentiate into hepatocytes in vitro and in vivo. MSCs administration could repair injured …

Liver fibrosis is a common result of most chronic liver diseases, and advanced fibrosis often
leads to cirrhosis. Currently, there is no effective treatment for liver cirrhosis except liver …

Background Mesenchymal stem cells (MSCs) are a valuable cell source in regenerative
medicine. Recently, several studies have shown that MSCs can be easily isolated from …

End‐stage liver fibrosis frequently progresses to portal vein thrombosis, formation of
oesophageal varices, hepatic encephalopathy, ascites, hepatocellular carcinoma and liver …

Abstract Background: The extracellular vesicles (EVs) secreted by bone marrow-derived
mesenchymal stem cells (MSCs) hold significant potential as a novel alternative to whole …

The therapeutic potential of mesenchymal stromal cells (MSCs) in the treatment of liver
fibrosis is predominantly based on their immunosuppressive properties, and their ability to …