Influence of a Hydroxyl Group on the Deamidation and Dehydration Reactions of Protonated Asparagine-Serine Investigated by Combined Spectroscopic, Guided Ion …
GC Boles, LJM Kempkes, J Martens… - Journal of the …, 2021 - ACS Publications
Deamidation of asparaginyl (Asn) peptides is a spontaneous post-translational modification
that plays a significant role in degenerative diseases and other biological processes under …
that plays a significant role in degenerative diseases and other biological processes under …
Deamidation of protonated asparagine–valine investigated by a combined spectroscopic, guided ion beam, and theoretical study
LJM Kempkes, GC Boles, J Martens… - The Journal of …, 2018 - ACS Publications
Peptide deamidation of asparaginyl residues is a spontaneous post-translational
modification that is believed to play a role in aging and several diseases. It is also a well …
modification that is believed to play a role in aging and several diseases. It is also a well …
Ion spectroscopy and guided ion beam studies of protonated asparaginyl-threonine decomposition: Influence of a hydroxyl containing C-Terminal residue on …
The spontaneous deamidation of asparagine residues plays a significant role in various
biological functions and degenerative, aging diseases. Here, we present a full description of …
biological functions and degenerative, aging diseases. Here, we present a full description of …
Thermodynamics and mechanisms of protonated asparaginyl-glycine decomposition
GC Boles, RR Wu, MT Rodgers… - The Journal of Physical …, 2016 - ACS Publications
Deamidation at asparagine residues, a spontaneous post-translational modification in
proteins, plays a significant role in various biological processes and degenerative diseases …
proteins, plays a significant role in various biological processes and degenerative diseases …
Protonated asparaginyl-alanine decomposition: a TCID, SORI-CID, and computational analysis
GC Boles, RR Wu, MT Rodgers… - Journal of The …, 2018 - ACS Publications
Deamidation of asparagine residues, one of the fastest known post-translational
modifications in proteins, plays a significant role in various biological functions and …
modifications in proteins, plays a significant role in various biological functions and …
Thermodynamics and mechanism of protonated asparagine decomposition
AL Heaton, PB Armentrout - Journal of the American Society for …, 2011 - ACS Publications
Deamidation of the amino acid asparagine (Asn) is a primary route for spontaneous post-
translational protein modification biologically and is a pH dependent process. Here we …
translational protein modification biologically and is a pH dependent process. Here we …
Thermodynamics and mechanism of the deamidation of sodium-bound asparagine
AL Heaton, PB Armentrout - Journal of the American Chemical …, 2008 - ACS Publications
The deamidation of asparagine (Asn) residues is the most common type of spontaneous
post-translational protein modification and plays a vital role in inflammation, protein …
post-translational protein modification and plays a vital role in inflammation, protein …
Deamidation reactions of asparagine-and glutamine-containing dipeptides investigated by ion spectroscopy
LJM Kempkes, J Martens, J Grzetic… - Journal of The …, 2016 - ACS Publications
Deamidation is a major fragmentation channel upon activation by collision induced
dissociation (CID) for protonated peptides containing glutamine (Gln) and asparagine (Asn) …
dissociation (CID) for protonated peptides containing glutamine (Gln) and asparagine (Asn) …
Deamidation reactions of protonated asparagine and glutamine investigated by ion spectroscopy
LJM Kempkes, JK Martens, J Grzetic… - Rapid …, 2016 - Wiley Online Library
Rationale Deamidation of Asn and Gln residues is a primary route for spontaneous post‐
translational protein modification. Several structures have been proposed for the …
translational protein modification. Several structures have been proposed for the …
Energetics and mechanisms for decomposition of cationized amino acids and peptides explored using guided ion beam tandem mass spectrometry
PB Armentrout - Mass Spectrometry Reviews, 2023 - Wiley Online Library
Fragmentation studies of cationized amino acids and small peptides as studied using
guided ion beam tandem mass spectrometry (GIBMS) are reviewed. After a brief …
guided ion beam tandem mass spectrometry (GIBMS) are reviewed. After a brief …
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- ion beam combined spectroscopic
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- ion beam mechanisms for decomposition
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- ion beam energetics and mechanisms