Anastomotic intimal hyperplasia and surface thrombogenicity are the main reasons for the
high failure rate of prosthetic small‐diameter vascular grafts. While anastomotic intimal …

Tissue engineering has garnered significant attention for its potential to address the
predominant modes of failure of small diameter vascular prostheses, namely mid-graft …

abstract A persistent clinical demand exists for a suitable arterial prosthesis. In this study, a
vascular conduit mimicking the native 3-layered artery, and constructed from the …

For patients with severe coronary artery and distal peripheral vascular disease not
amenable to angioplasty and lacking sufficient autologous vessels there is a pressing need …

Background There is a considerable clinical need for a sufficient prosthetic small-diameter
substitute which can compete with autologous vessels. Currently used synthetic materials …

Vascular tissue engineering has the potential to make a significant impact on the treatment
of a wide variety of medical conditions, including providing in vitro generated vascularized …

Vascular disease results in the decreased utility and decreased availability of autologus
vascular tissue for small diameter (< 6 mm) vessel replacements. While synthetic polymer …

Despite the wide variety of tissue‐engineered vascular grafts that are currently being
developed, autologous vessels, such as the saphenous vein, are still the gold standard …

Small diameter (< 6 mm) vascular grafts are in large demand for coronary and peripheral
bypass procedures. Although synthetic grafts have been developed, tissue-based vascular …

Over the last 20 years, a diverse number of different approaches have been explored in
trying to produce engineered tissue vascular grafts (ETVGs). If successful, this alternative …