Developing Plasma-Based Diagnostics: From Pancreatic Ductal Adenocarcinoma to HIV

A Makler - 2023 - search.proquest.com
Plasma-based diagnostics are ideal for detecting a variety of diseases because they offer a
method of detection that is minimally invasive, readily available, and easy to use for …

Exosomal miRNA biomarker panel for pancreatic ductal adenocarcinoma detection in patient plasma: a pilot study

A Makler, W Asghar - International Journal of Molecular Sciences, 2023 - mdpi.com
Pancreatic ductal adenocarcinoma (PDAC) is rapidly becoming one of the leading causes of
cancer-related deaths in the United States, and with its high mortality rate, there is a …

[HTML][HTML] Emerging Horizons in the Diagnosis of Pancreatic Cancer: The Role of Circulating microRNAs as Early Detection Biomarkers for Pancreatic Ductal …

I Reyaz, B Khan, N James, H Azhar, A Rehman… - Cureus, 2024 - ncbi.nlm.nih.gov
Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive cancer with a poor
prognosis, primarily due to a late diagnosis. Recent studies have focused on identifying non …

An exosomal miRNA biomarker for the detection of pancreatic ductal adenocarcinoma

A Makler, R Narayanan, W Asghar - Biosensors, 2022 - mdpi.com
Pancreatic ductal adenocarcinoma (PDAC) remains a difficult tumor to diagnose and treat.
To date, PDAC lacks routine screening with no markers available for early detection …

Emerging Therapeutic Options in Pancreatic Cancer Management

D Delle Cave - International Journal of Molecular Sciences, 2024 - mdpi.com
Pancreatic ductal adenocarcinoma (PDAC) is a devastating disease with a 5-year survival
rate of< 8%[1–3]. PDAC is characterized by dense desmoplastic stroma, which can …

Abstract PO-007: Plasma-based detection of pancreatic cancer: A multiomics approach

TK Hsu, TY Liu, B Gould, C Decapite, A Zureikat… - Cancer Research, 2021 - AACR
Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers, with an overall
five-year survival rate of 11%. Potential curative resection is possible if the tumor is detected …

Tumor-specific miRNA signatures in combination with CA19-9 for liquid biopsy-based detection of PDAC

MW Kim, H Koh, JY Kim, S Lee, H Lee, Y Kim… - International Journal Of …, 2021 - mdpi.com
Pancreatic ductal adenocarcinoma (PDAC) is considered one of the most aggressive
malignancies and has high mortality and poor survival rates. Therefore, there is an urgent …

An exosomal miRNA-based liquid biopsy signature for the noninvasive early detection of pancreatic ductal adenocarcinoma

K Nakamura, S Roy, Z Zhu, E Jun, H Han, RM Munoz… - Cancer Research, 2022 - AACR
Background: Pancreatic ductal adenocarcinoma (PDAC) is projected to become the second
leading cause of cancer-related deaths in the United States by 2030. Most of the PDAC …

miR‑3940‑5p/miR‑8069 ratio in urine exosomes is a novel diagnostic biomarker for pancreatic ductal adenocarcinoma

N Yoshizawa, K Sugimoto, M Tameda… - Oncology …, 2020 - spandidos-publications.com
Despite the development of several therapeutic options, the prognosis of pancreatic cancer
remains poor. One reason for this is the difficulty of diagnosing the disease at an early stage …

An exosome-based transcriptomic signature for noninvasive, early detection of patients with pancreatic ductal adenocarcinoma: a multicenter cohort study

K Nakamura, Z Zhu, S Roy, E Jun, H Han, RM Munoz… - Gastroenterology, 2022 - Elsevier
Abstract Background & Aims Pancreatic ductal adenocarcinoma (PDAC) incidence is rising
worldwide, and most patients present with an unresectable disease at initial diagnosis …