Autologous stem cell transplantation with or without in vitro lymphocyte depletion has been
suggested as a new treatment option for severe autoimmune diseases. We describe five …

Background Autologous hematopoietic stem cell transplantation has been used since 1996
for the treatment of severe autoimmune diseases refractory to approved therapies. We …

Abstract Since Morton and Siegel's epochal experiments 30 years ago animal models have
been successfully utilized both for transfer and resolution of autoimmune diseases (AID) …

An extensive series of experimental investigations has shown that both inherited and
induced autoimmune diseases in laboratory animals may be transferred and, conversely …

Since 1996, approximately 1,000 patients have received an autologous hematopoietic stem
cell transplant (HSCT) as treatment for a severe autoimmune disease (AD). The European …

To determine the role of allogeneic, autologous and syngeneic hemopoietic stem cell
transplantation (SCTx) as a treatment for severe autoimmune disease (AID) we performed a …

This ongoing multicentre prospective phase I/II trial enrolled 74 consecutive patients from 22
centres worldwide with severe autoimmune disease, 35 with rheumatological disorders, 31 …

Hematopoietic stem cell transplantation (HSCT) is being increasingly utilized for the
treatment of a whole spectrum of severe autoimmune diseases refractory to conventional …

Allogeneic hematopoietic SCT (HSCT) has been used as treatment for single patients with
autoimmune diseases (AD). To summarise currently available information, we analyzed all …

Multiple sclerosis, systemic lupus erythematosus, and rheumatoid arthritis are immune-
mediated diseases that are responsive to suppression or modulation of the immune system …