Stochastic models inspired by hybridization theory for short oligonucleotide arrays

Z Wu, RA Irizarry - Proceedings of the eighth annual international …, 2004 - dl.acm.org
High density oligonucleotide expression arrays are a widely used tool for the measurement
of gene expression on a large scale. Affymetrix GeneChip arrays appear to dominate this …

A model-based background adjustment for oligonucleotide expression arrays

Z Wu, RA Irizarry, R Gentleman… - Journal of the …, 2004 - Taylor & Francis
High-density oligonucleotide expression arrays are widely used in many areas of
biomedical research. Affymetrix GeneChip arrays are the most popular. In the Affymetrix …

Statistical analysis of high-density oligonucleotide arrays: a multiplicative noise model

R Šášik, E Calvo, J Corbeil - Bioinformatics, 2002 - academic.oup.com
Motivation: High-density oligonucleotide arrays (GeneChip, Affymetrix, Santa Clara, CA)
have become a standard research tool in many areas of biomedical research. They …

Model-based analysis of oligonucleotide arrays: expression index computation and outlier detection

C Li, WH Wong - Proceedings of the National Academy of …, 2001 - National Acad Sciences
Recent advances in cDNA and oligonucleotide DNA arrays have made it possible to
measure the abundance of mRNA transcripts for many genes simultaneously. The analysis …

Summaries of Affymetrix GeneChip probe level data

RA Irizarry, BM Bolstad, F Collin, LM Cope… - Nucleic acids …, 2003 - academic.oup.com
High density oligonucleotide array technology is widely used in many areas of biomedical
research for quantitative and highly parallel measurements of gene expression. Affymetrix …

Theoretical and experimental comparisons of gene expression indexes for oligonucleotide arrays

WJ Lemon, JJT Palatini, R Krahe, FA Wright - Bioinformatics, 2002 - academic.oup.com
Motivation: Oligonucleotide expression arrays exhibit systematic and reproducible variation
produced by the multiple distinct probes used to represent a gene. Recently, a gene …

Probe selection for high-density oligonucleotide arrays

R Mei, E Hubbell, S Bekiranov… - Proceedings of the …, 2003 - National Acad Sciences
High-density oligonucleotide microarrays enable simultaneous monitoring of expression
levels of tens of thousands of transcripts. For accurate detection and quantitation of …

A systematic statistical linear modeling approach to oligonucleotide array experiments

TM Chu, B Weir, R Wolfinger - Mathematical biosciences, 2002 - Elsevier
We outline and describe steps for a statistically rigorous approach to analyzing probe-level
Affymetrix GeneChip data. The approach employs classical linear mixed models and …

[HTML][HTML] Exon arrays provide accurate assessments of gene expression

K Kapur, Y Xing, Z Ouyang, WH Wong - Genome biology, 2007 - Springer
We have developed a strategy for estimating gene expression on Affymetrix Exon arrays.
The method includes a probe-specific background correction and a probe selection strategy …

Absolute mRNA concentrations from sequence‐specific calibration of oligonucleotide arrays

D Hekstra, AR Taussig, M Magnasco… - Nucleic acids …, 2003 - academic.oup.com
Oligonucleotide microarrays are based on the hybridization of labeled mRNA molecules to
short length oligonucleotide probes on a glass surface. Two effects have been shown to …