To explore the contribution of functional coding variants to psoriasis, we analyzed
nonsynonymous single-nucleotide variants (SNVs) across the genome by exome …

In a previous large-scale exome sequencing analysis for psoriasis, we discovered seven
common and low-frequency missense variants within six genes with genome-wide …

Genome-wide association studies (GWASs) have reproducibly associated∼ 40
susceptibility loci with psoriasis. However, the missing heritability is evident and the …

We carried out a meta-analysis of two recent psoriasis genome-wide association studies,
with a combined discovery sample of 1,831 affected individuals (cases) and 2,546 controls …

We report the first large genome-wide association study (GWAS) in a Chinese population to
identify susceptibility variants for psoriasis using a two-stage case-control design. In the first …

We extended our previous genome-wide association study for psoriasis with a multistage
replication study including 8,312 individuals with psoriasis (cases) and 12,919 controls from …

Psoriasis is a common immune-mediated disorder that affects the skin, nails and joints. To
identify psoriasis susceptibility loci, we genotyped 438,670 SNPs in 1,409 psoriasis cases …

Psoriasis is a multifactorial skin disease characterized by epidermal hyperproliferation and
chronic inflammation, the most common form of which is psoriasis vulgaris (PsV). We …

Psoriasis is a complex disease of skin with a prevalence of about 2%. We conducted the
largest meta-analysis of genome-wide association studies (GWAS) for psoriasis to date …

To gain further insight into the genetic architecture of psoriasis, we conducted a meta-
analysis of 3 genome-wide association studies (GWAS) and 2 independent data sets …