Substitutions are boring: some arguments about parallel mutations and repetitive DNA
Extant genomes are largely shaped by the global transposition, copy number fluctuation,
and rearrangement of DNA sequences, rather than by the substitutions of single nucleotides …
and rearrangement of DNA sequences, rather than by the substitutions of single nucleotides …
Substitutions are boring: some arguments about parallel mutations and high mutation rates
Extant genomes are largely shaped by global transposition, copy-number fluctuation, and
rearrangement of DNA sequences rather than by substitutions of single nucleotides …
rearrangement of DNA sequences rather than by substitutions of single nucleotides …
For genomes, repetition breeds diversity
R Robinson - PLoS Biology, 2011 - journals.plos.org
A long-time observation in genomes from bacteria to humans is that the level of nucleotide
diversity varies from region to region within the genome. The sequence at some spots is …
diversity varies from region to region within the genome. The sequence at some spots is …
Clusters of nucleotide substitutions and insertion/deletion mutations are associated with repeat sequences
The genome-sequencing gold rush has facilitated the use of comparative genomics to
uncover patterns of genome evolution, although their causal mechanisms remain elusive …
uncover patterns of genome evolution, although their causal mechanisms remain elusive …
Repetitive DNA sequences
Repetitive DNAs are ubiquitous in eukaryotic genomes and, in many species, comprise the
bulk of the genome. Repeats include transposable elements that can self-mobilize and …
bulk of the genome. Repeats include transposable elements that can self-mobilize and …
Mutation rate variation in eukaryotes: evolutionary implications of site-specific mechanisms
DG King, Y Kashi - Nature Reviews Genetics, 2007 - nature.com
Baer et al.'s Review “Mutation rate variation in multicellular eukaryotes: causes and
consequences” 1 accurately conveys the tenor of most literature on mutation rate evolution …
consequences” 1 accurately conveys the tenor of most literature on mutation rate evolution …
[图书][B] Repetitive DNA, genome evolution, and the adaptive evolution of mutation rates
DL Metzgar - 2001 - search.proquest.com
Tandemly repetitive DNAs of all motif lengths exhibit unique evolutionary properties that are
not shared by nonrepetitive sequences. These include hypermutability and a unique …
not shared by nonrepetitive sequences. These include hypermutability and a unique …
Widespread recurrent evolution of genomic features
The recent explosion of genome sequences from all major phylogenetic groups has
unveiled an unexpected wealth of cases of recurrent evolution of strikingly similar genomic …
unveiled an unexpected wealth of cases of recurrent evolution of strikingly similar genomic …
[图书][B] Repetitive DNA Sequences
Repetitive DNA is ubiquitous in eukaryotic genomes, and, in many species, comprises the
bulk of the genome. Repeats include transposable elements that can self-mobilize and …
bulk of the genome. Repeats include transposable elements that can self-mobilize and …
Tandemly repeated DNA: why should anyone care?
JAL Armour - … Research/Fundamental and Molecular Mechanisms of …, 2006 - Elsevier
Recent excitement over SNPs has tended to obscure the real advantages of studying
tandemly repeated loci. In this commentary, I make the case for studying tandem repeats …
tandemly repeated loci. In this commentary, I make the case for studying tandem repeats …