Renin–angiotensin–aldosterone system inhibitors and risk of Covid-19

HR Reynolds, S Adhikari, C Pulgarin… - … England Journal of …, 2020 - Mass Medical Soc
Background There is concern about the potential of an increased risk related to medications
that act on the renin–angiotensin–aldosterone system in patients exposed to coronavirus …

Renin–angiotensin–aldosterone system blockers and the risk of Covid-19

G Mancia, F Rea, M Ludergnani… - New England Journal …, 2020 - Mass Medical Soc
Background A potential association between the use of angiotensin-receptor blockers
(ARBs) and angiotensin-converting–enzyme (ACE) inhibitors and the risk of coronavirus …

Use of renin–angiotensin–aldosterone system inhibitors and risk of COVID-19 requiring admission to hospital: a case-population study

FJ de Abajo, S Rodríguez-Martín, V Lerma… - The Lancet, 2020 - thelancet.com
Background Concerns have been raised about the possibility that inhibitors of the renin–
angiotensin–aldosterone system (RAAS) could predispose individuals to severe COVID-19; …

Association of angiotensin-converting enzyme inhibitor or angiotensin receptor blocker use with COVID-19 diagnosis and mortality

EL Fosbøl, JH Butt, L Østergaard, C Andersson… - Jama, 2020 - jamanetwork.com
Importance It has been hypothesized that angiotensin-converting enzyme inhibitors
(ACEIs)/angiotensin receptor blockers (ARBs) may make patients more susceptible to …

Antihypertensive drugs and COVID-19 risk: a cohort study of 2 million hypertensive patients

L Semenzato, J Botton, J Drouin, B Baricault… - …, 2021 - Am Heart Assoc
After initially hypothesizing a positive relationship between use of renin-angiotensin-
aldosterone system inhibitors and risk of coronavirus disease 2019 (COVID-19), more recent …

[HTML][HTML] Renin–angiotensin system blockers and susceptibility to COVID-19: an international, open science, cohort analysis

DR Morales, MM Conover, SC You, N Pratt… - The Lancet Digital …, 2021 - thelancet.com
Background Angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor
blockers (ARBs) have been postulated to affect susceptibility to COVID-19. Observational …

Estimation of renin-angiotensin-aldosterone-system (RAAS)-inhibitor effect on COVID-19 outcome: a meta-analysis

CJ Pirola, S Sookoian - Journal of Infection, 2020 - Elsevier
Background and rationale Some studies of hospitalized patients suggested that the risk of
death and/or severe illness due to COVID-19 is not associated with the use of angiotensin …

[HTML][HTML] Renin–angiotensin–aldosterone system inhibitors and risk of death in patients hospitalised with COVID-19: a retrospective Italian cohort study of 43,000 …

G Trifirò, M Massari, R Da Cas, F Menniti Ippolito… - Drug Safety, 2020 - Springer
Introduction The epidemic due to severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) infection has been spreading globally, raising increasing concerns. There are …

Hypertension, medications, and risk of severe COVID‐19: a Massachusetts community‐based observational study

AZ Bauer, R Gore, SR Sama, R Rosiello… - The Journal of …, 2021 - Wiley Online Library
It remains uncertain whether the hypertension (HT) medications angiotensin‐converting
enzyme inhibitors (ACEi) and angiotensin receptor blockers (ARB) mitigate or exacerbate …

Association between renin-angiotensin-aldosterone system inhibitors and clinical outcomes in patients with COVID-19: a systematic review and meta-analysis

R Baral, V Tsampasian, M Debski, B Moran… - JAMA network …, 2021 - jamanetwork.com
Importance The chronic receipt of angiotensin-converting enzyme inhibitors (ACEIs) and
angiotensin receptor blockers (ARBs) has been assumed to exacerbate complications …