Vicarious social defeat stress induces depression-related outcomes in female mice
Background Stress is a prevailing risk factor for mood-related illnesses, wherein women
represent the majority of those affected by major depression. Despite the growing literature …
represent the majority of those affected by major depression. Despite the growing literature …
Establishment of a repeated social defeat stress model in female mice
A Takahashi, JR Chung, S Zhang, H Zhang… - Scientific reports, 2017 - nature.com
Numerous studies have employed repeated social defeat stress (RSDS) to study the
neurobiological mechanisms of depression in rodents. An important limitation of RSDS …
neurobiological mechanisms of depression in rodents. An important limitation of RSDS …
Fighting females: neural and behavioral consequences of social defeat stress in female mice
Background Despite the twofold higher prevalence of major depressive and posttraumatic
stress disorders in women compared with men, most clinical and preclinical studies have …
stress disorders in women compared with men, most clinical and preclinical studies have …
Chronic non-discriminatory social defeat is an effective chronic stress paradigm for both male and female mice
Stress-related mood disorders are more prevalent in females than males, yet preclinical
chronic stress paradigms were developed in male rodents and are less effective in female …
chronic stress paradigms were developed in male rodents and are less effective in female …
Neurobiological sequelae of witnessing stressful events in adult mice
BACKGROUND: It is well known that exposure to severe stress increases the risk for
developing mood disorders. However, most chronic stress models in rodents involve at least …
developing mood disorders. However, most chronic stress models in rodents involve at least …
Vicarious social defeat stress: Bridging the gap between physical and emotional stress
Background Animal models capable of differentiating the neurobiological intricacies
between physical and emotional stress are scarce. Current models rely primarily on physical …
between physical and emotional stress are scarce. Current models rely primarily on physical …
Social defeat stress induces a depression-like phenotype in adolescent male c57BL/6 mice
Exposure to stress is highly correlated with the emergence of mood-related illnesses.
Because major depressive disorder often emerges in adolescence, we assessed the effects …
Because major depressive disorder often emerges in adolescence, we assessed the effects …
Can I get a witness? Using vicarious defeat stress to study mood-related illnesses in traditionally understudied populations
BL Warren, MS Mazei-Robison, AJ Robison… - Biological …, 2020 - Elsevier
The chronic social defeat stress model has been instrumental in shaping our understanding
of neurobiology relevant to affect-related illnesses, including major depressive disorder …
of neurobiology relevant to affect-related illnesses, including major depressive disorder …
Chronic social defeat stress in female mice leads to sex-specific behavioral and neuroendocrine effects
L van Doeselaar, H Yang, J Bordes, L Brix… - Stress, 2021 - Taylor & Francis
Over the years, it has become increasingly clear that males and females respond differently
towards environmental stressors, highlighting the importance of including both sexes when …
towards environmental stressors, highlighting the importance of including both sexes when …
A novel method for chronic social defeat stress in female mice
Historically, preclinical stress studies have often omitted female subjects, despite evidence
that women have higher rates of anxiety and depression. In rodents, many stress …
that women have higher rates of anxiety and depression. In rodents, many stress …