OBJECTIVE: To test whether annual screening with transvaginal ultrasonography and CA
125 reduces ovarian cancer mortality. METHODS: Data from the first four annual screens …

Importance Ovarian cancer is relatively rare but the fifth-leading cause of cancer mortality
among United States women. Objective To systematically review evidence on benefits and …

Background The value of screening for ovarian cancer is uncertain. We did a pilot
randomised trial to assess multimodal screening with sequential CA 125 antigen and …

OBJECTIVE: Ovarian cancer screening with transvaginal ultrasound (TVU) and CA-125 was
evaluated in the Prostate, Lung, Colorectal and Ovarian (PLCO) Trial. STUDY DESIGN: This …

Objective We performed a systematic review and meta-analysis to quantify risks and benefits
of screening asymptomatic women for ovarian cancer. Methods We searched MEDLINE …

Purpose: To critically review the available evidence for screening asymptomatic women for
ovarian cancer with ultrasonography or the CA 125 radioimmunoassay (CA 125) or both …

DISCUSSION Ovarian cancer is the fifth leading cause of cancer death among women in the
US, accounting for an estimated 25,400 new cases and 14,300 deaths in 2003. 3 Several …

Objective To estimate the performance of currently available tests in detecting ovarian
cancer in asymptomatic women. Methods Systematic review of prospective screening …

Context Screening for ovarian cancer with cancer antigen 125 (CA-125) and transvaginal
ultrasound has an unknown effect on mortality. Objective To evaluate the effect of screening …

There has been considerable interest in the prospect of early detection of ovarian cancer
through screening asymptomatic women, in both the general and 'high-risk'populations …