Oxytocin directly administered into the nucleus accumbens core or subthalamic nucleus attenuates methamphetamine-induced conditioned place preference

SJ Baracz, PI Rourke, MC Pardey, GE Hunt… - Behavioural brain …, 2012 - Elsevier
Accumulating evidence indicates that the neuropeptide oxytocin (OXY) may modulate
reward-related behavioural responses to methamphetamine (METH) administration. Limited …

Effects of oxytocin on methamphetamine-induced conditioned place preference and the possible role of glutamatergic neurotransmission in the medial prefrontal …

J Qi, JY Yang, F Wang, YN Zhao, M Song, CF Wu - Neuropharmacology, 2009 - Elsevier
Accumulating evidence has shown the neuroactive properties of oxytocin (OT), a
neurohypophyseal neuropeptide, and its ability to reduce the abuse potential of drugs. The …

Oxytocin enhances the expression of morphine-induced conditioned place preference in rats

M Moaddab, BI Hyland, CH Brown - Psychoneuroendocrinology, 2015 - Elsevier
Drug addiction is characterized by drug-seeking and drug-taking and has devastating
consequences on addicts as well as on society. Environmental contexts previously …

Oxytocin treatment in the prelimbic cortex reduces relapse to methamphetamine-seeking and is associated with reduced activity in the rostral nucleus accumbens core

N Everett, S Baracz, J Cornish - Pharmacology Biochemistry and Behavior, 2019 - Elsevier
Addiction to the psychostimulant Methamphetamine (METH) is characterised by high rates of
relapse. Currently there are no approved effective pharmacotherapies for METH …

Oxytocin in the nucleus accumbens core reduces reinstatement of methamphetamine‐seeking behaviour in rats

SJ Baracz, NA Everett, IS McGregor… - Addiction …, 2016 - Wiley Online Library
The psychostimulant methamphetamine (METH) is an addictive illicit drug. Systemic
administration of the neuropeptide oxytocin modulates METH‐related reward and METH …

Oxytocin via its receptor affects restraint stress-induced methamphetamine CPP reinstatement in mice: Involvement of the medial prefrontal cortex and dorsal …

WY Han, P Du, SY Fu, F Wang, M Song, CF Wu… - Pharmacology …, 2014 - Elsevier
Our previous study revealed that intracerebroventricular oxytocin (OT) markedly inhibited the
restraint stress-priming conditioned place preference (CPP) reinstatement induced by …

Repeated oxytocin treatment during abstinence inhibited context-or restraint stress-induced reinstatement of methamphetamine-conditioned place preference and …

J Cai, X Che, T Xu, Y Luo, M Yin, X Lu, C Wu… - Experimental …, 2022 - Elsevier
Propensity to relapse, even after long-term abstinence, is a crucial feature of
methamphetamine (METH) abuse. We and other laboratories have reported that acute …

Chronic methamphetamine self‐administration dysregulates oxytocin plasma levels and oxytocin receptor fibre density in the nucleus accumbens core and …

SJ Baracz, LM Parker, AS Suraev… - Journal of …, 2016 - Wiley Online Library
The neuropeptide oxytocin attenuates reward and abuse for the psychostimulant
methamphetamine (METH). Recent findings have implicated the nucleus accumbens (NA c) …

[HTML][HTML] The involvement of oxytocin in the subthalamic nucleus on relapse to methamphetamine-seeking behaviour

SJ Baracz, NA Everett, JL Cornish - PloS one, 2015 - journals.plos.org
The psychostimulant methamphetamine (METH) is an addictive drug of abuse. The
neuropeptide oxytocin has been shown to modulate METH-related reward and METH …

The vagus nerve mediates the suppressing effects of peripherally administered oxytocin on methamphetamine self-administration and seeking in rats

NA Everett, AJ Turner, PA Costa, SJ Baracz… - …, 2021 - nature.com
The neuropeptide oxytocin has emerged as a promising pharmacotherapy for
methamphetamine (METH) addiction, and clinical trials of intranasal oxytocin are underway …