Background The Partners HSV-2/HIV-1 Transmission Study (Partners Study) is a phase III,
placebo-controlled trial of daily acyclovir for genital herpes (HSV-2) suppression among HIV …

Introduction More new HIV-1 infections occur within stable HIV-1-discordant couples than in
any other group in Africa, and sexually transmitted infections (STIs) may increase …

Background. Daily suppressive therapy with valacyclovir reduces risk of sexual transmission
of herpes simplex virus type 2 (HSV-2) in HSV-2–serodiscordant heterosexual couples by …

Background Most HIV-1 transmission in Africa occurs among HIV-1-discordant couples (one
partner HIV-1 infected and one uninfected) who are unaware of their discordant HIV-1 …

Objective: To determine risk factors for HIV transmission within married couples in four urban
populations in sub-Saharan Africa. Methods: Data from a cross-sectional population-based …

Objectives A large proportion of new HIV infections in sub‐Saharan Africa occur in stable
HIV‐discordant partnerships. In some couples, the strong desire to conceive a child may …

Objective: Effective behavioral HIV prevention is needed for stable HIV-discordant couples
at risk for HIV, especially those without access to biomedical prevention. This analysis …

Background The risk of sexual HIV transmission in serodiscordant couples when the HIV-
positive partner has full virologic suppression on combination antiretroviral therapy (cART) is …

Objective Recent randomised clinical trials among stable HIV sero-discordant couples
(SDCs) in sub-Saharan Africa (SSA) have reported that about 20–30% of new HIV infections …

Background Most persons who are infected with human immunodeficiency virus type 1 (HIV-
1) are also infected with herpes simplex virus type 2 (HSV-2), which is frequently reactivated …