Invasion and migration of MDA‐MB‐231 cells are inhibited by block of AhR and NFAT: role of AhR/NFAT1/β4 integrin signaling

A Shadboorestan, GA Tarfiei… - Journal of Applied …, 2019 - Wiley Online Library
Abstract Benzo [α] pyrene (BaP) can have significant role in the development of breast
cancer via aryl hydrocarbon receptor (AhR) activation. AhR activation has been studied in …

Benzo-[a]-pyrene induces FAK activation and cell migration in MDA-MB-231 breast cancer cells

R Castillo-Sanchez, S Villegas-Comonfort… - Cell biology and …, 2013 - Springer
Abstract Benzo-[a]-pyrene (B [a] P) is a family member of polycyclic aromatic hydrocarbons
and a widespread environmental pollutant. It is a mammary carcinogen in rodents and …

Benzo-[a]-pyrene increases invasion in MDA-MB-231 breast cancer cells via increased COX-II expression and prostaglandin E2 (PGE2) output

ME Miller, AC Holloway, WG Foster - Clinical & experimental metastasis, 2005 - Springer
Abstract Benzo-[a]-pyrene (B [a] P), a carcinogenic component of cigarette smoke, has been
shown to increase both COX-II expression and prostaglandin output in vascular smooth …

Hexachlorobenzene modulates the crosstalk between the aryl hydrocarbon receptor and transforming growth factor-β1 signaling, enhancing human breast cancer cell …

N Miret, C Pontillo, C Ventura, A Carozzo, F Chiappini… - Toxicology, 2016 - Elsevier
Given the number of women affected by breast cancer, considerable interest has been
raised in understanding the relationships between environmental chemicals and disease …

Bisphenol A induces migration through a GPER-, FAK-, Src-, and ERK2-dependent pathway in MDA-MB-231 breast cancer cells

R Castillo Sanchez, R Gomez… - Chemical research in …, 2016 - ACS Publications
Bisphenol A (BPA) is an industrial synthetic chemical utilized in the production of numerous
products including food and beverage containers. Humans are exposed to BPA during …

Effects of Benzoapyrene on migration and invasion of lung cancer cells functioning by TNF‐α

G Zhao, Z Wang, Y Huang, L Ye, K Yang… - Journal of Cellular …, 2018 - Wiley Online Library
In this study, we attempted to find out the underlying mechanism of Benzoapyrene and
metastasis of lung cancer cells. We also did experiments to testify the connection between …

Benzo (a) pyrene affects proliferation with reference to metabolic genes and ROS/HIF-1α/HO-1 signaling in A549 and MCF-7 cancer cells

M Gao, A Zheng, L Chen, F Dang, X Liu… - Drug and chemical …, 2022 - Taylor & Francis
Abstract Benzo (a) pyrene (BaP) is a representative polycyclic aromatic hydrocarbon (PAH)
compound, which has been implicated in cancer initiation and promotion. Although BaP is …

Angiogenesis signaling in breast cancer models is induced by hexachlorobenzene and chlorpyrifos, pesticide ligands of the aryl hydrocarbon receptor

LV Zárate, CA Pontillo, A Español, NV Miret… - Toxicology and Applied …, 2020 - Elsevier
Breast cancer incidence is increasing globally and pesticides exposure may impact risk of
developing this disease. Hexachlorobenzene (HCB) and chlorpyrifos (CPF) act as …

Diallyl trisulfide inhibits cell migration and invasion of human melanoma a375 cells via inhibiting integrin/facal adhesion kinase pathway

HC Wang, YL Chu, SC Hsieh… - Environmental …, 2017 - Wiley Online Library
Melanoma is the leading cause of death from skin disease due to its propensity for
metastasis. Studies have shown that integrin‐mediated focal adhesion kinase (FAK) signal …

Dihydroavenanthramide D inhibits human breast cancer cell invasion through suppression of MMP-9 expression

YR Lee, EM Noh, HJ Oh, H Hur, JM Kim, JH Han… - Biochemical and …, 2011 - Elsevier
Dihydroavenanthramide D (DHAvD) is a synthetic analog to naturally occurring
avenanthramide, which is the active component of oat. Previous study demonstrates that …