[HTML][HTML] Variation in use of erythrocyte invasion pathways by Plasmodium falciparum mediates evasion of human inhibitory antibodies

KEM Persson, FJ McCallum, L Reiling… - The Journal of …, 2008 - Am Soc Clin Investig
Antibodies that inhibit Plasmodium falciparum invasion of erythrocytes are believed to be an
important component of immunity against malaria. During blood-stage infection, P …

Antibodies to Reticulocyte Binding Protein-Like Homologue 4 Inhibit Invasion of Plasmodium falciparum into Human Erythrocytes

WH Tham, DW Wilson, L Reiling, L Chen… - Infection and …, 2009 - Am Soc Microbiol
Plasmodium falciparum invasion into human erythrocytes relies on the interaction between
multiple parasite ligands and their respective erythrocyte receptors. The sialic acid …

Expression of Plasmodium falciparum genes involved in erythrocyte invasion varies among isolates cultured directly from patients

S Nery, AM Deans, M Mosobo, K Marsh… - Molecular and …, 2006 - Elsevier
Plasmodium falciparum merozoites invade erythrocytes using a range of alternative ligands
that includes erythrocyte binding antigenic proteins (EBAs) and reticulocyte binding protein …

Erythrocyte Invasion Phenotypes of Plasmodiumfalciparum in The Gambia

J Baum, M Pinder, DJ Conway - Infection and immunity, 2003 - Am Soc Microbiol
In vitro experimentation with Plasmodium falciparum has determined that a number of
different receptor-ligand interactions are involved in the invasion of erythrocytes. Most …

Plasmodium falciparum field isolates use complement receptor 1 (CR1) as a receptor for invasion of erythrocytes

GA Awandare, C Spadafora, JK Moch, S Dutta… - Molecular and …, 2011 - Elsevier
A majority of Plasmodium falciparum strains invade erythrocytes through interactions with
sialic acid (SA) on glycophorins. However, we recently reported that complement receptor 1 …

[HTML][HTML] Targeting Sialic Acid Dependent and Independent Pathways of Invasion in Plasmodium falciparum

RL Ord, M Rodriguez, T Yamasaki, S Takeo, T Tsuboi… - PloS one, 2012 - journals.plos.org
The pathology of malaria is a consequence of the parasitaemia which develops through the
cyclical asexual replication of parasites in a patient's red blood cells. Multiple parasite ligand …

Erythrocyte-binding antigens of Plasmodium falciparum are targets of human inhibitory antibodies and function to evade naturally acquired immunity

KEM Persson, FJI Fowkes, FJ McCallum… - The Journal of …, 2013 - journals.aai.org
Abs that inhibit Plasmodium falciparum invasion of erythrocytes form an important
component of human immunity against malaria, but key target Ags are largely unknown …

Plasmodium falciparum Field Isolates Commonly Use Erythrocyte Invasion Pathways That Are Independent of Sialic Acid Residues of Glycophorin A

JN Okoyeh, CR Pillai, CE Chitnis - Infection and immunity, 1999 - Am Soc Microbiol
Erythrocyte invasion by malaria parasites is mediated by specific molecular interactions.
Sialic acid residues of glycophorin A are used as invasion receptors by Plasmodium …

Targeted disruption of an erythrocyte binding antigen in Plasmodium falciparum is associated with a switch toward a sialic acid-independent pathway of invasion

MB Reed, SR Caruana, AH Batchelor… - Proceedings of the …, 2000 - National Acad Sciences
Erythrocyte invasion by Plasmodium requires molecules present both on the merozoite
surface and within the specialized organelles of the apical complex. The Plasmodium …

Evidence for erythrocyte-binding antigen 175 as a component of a ligand-blocking blood-stage malaria vaccine

L Jiang, D Gaur, J Mu, H Zhou… - Proceedings of the …, 2011 - National Acad Sciences
The ligands that pathogens use to invade their target cells have often proven to be good
targets for vaccine development. However, Plasmodium falciparum has redundant ligands …