Codon identity regulates mRNA stability and translation efficiency during the maternal‐to‐zygotic transition

AA Bazzini, F Del Viso, MA Moreno‐Mateos… - The EMBO …, 2016 - embopress.org
Cellular transitions require dramatic changes in gene expression that are supported by
regulated mRNA decay and new transcription. The maternal‐to‐zygotic transition is a …

[HTML][HTML] Crosstalk between codon optimality and cis-regulatory elements dictates mRNA stability

SG Medina-Muñoz, G Kushawah, LA Castellano… - Genome biology, 2021 - Springer
Background The regulation of messenger RNA (mRNA) stability has a profound impact on
gene expression dynamics during embryogenesis. For example, in animals, maternally …

[HTML][HTML] Codon usage and 3′ UTR length determine maternal mRNA stability in zebrafish

Y Mishima, Y Tomari - Molecular cell, 2016 - cell.com
The control of mRNA stability plays a central role in regulating gene expression. In
metazoans, the earliest stages of development are driven by maternally supplied mRNAs …

[HTML][HTML] Codon and amino acid content are associated with mRNA stability in mammalian cells

ME Forrest, O Pinkard, S Martin, TJ Sweet, G Hanson… - PloS one, 2020 - journals.plos.org
Messenger RNA (mRNA) degradation plays a critical role in regulating transcript levels in
the cell and is a major control point for modulating gene expression. In yeast and other …

[HTML][HTML] Translation and mRNA stability control

Q Wu, AA Bazzini - Annual review of biochemistry, 2023 - annualreviews.org
Messenger RNA (mRNA) stability and translational efficiency are two crucial aspects of the
post-transcriptional process that profoundly impact protein production in a cell. While it is …

[HTML][HTML] Codon optimality is a major determinant of mRNA stability

V Presnyak, N Alhusaini, YH Chen, S Martin, N Morris… - Cell, 2015 - cell.com
Summary mRNA degradation represents a critical regulated step in gene expression.
Although the major pathways in turnover have been identified, accounting for disparate half …

[HTML][HTML] Translation affects mRNA stability in a codon-dependent manner in human cells

Q Wu, SG Medina, G Kushawah, ML DeVore… - elife, 2019 - elifesciences.org
mRNA translation decodes nucleotide into amino acid sequences. However, translation has
also been shown to affect mRNA stability depending on codon composition in model …

[HTML][HTML] Attenuated codon optimality contributes to neural-specific mRNA decay in Drosophila

DA Burow, S Martin, JF Quail, N Alhusaini, J Coller… - Cell reports, 2018 - cell.com
Tissue-specific mRNA stability is important for cell fate and physiology, but the mechanisms
involved are not fully understood. We found that zygotic mRNA stability in Drosophila …

Determinants of translational fidelity and efficiency in vertebrate mRNAs

M Kozak - Biochimie, 1994 - Elsevier
Determinants of translational fidelity and efficiency in vertebrate mRNAs Page 1 Biochimie (1994)
76, 815-82 l © Soc:i6t6 fran~aise de biochimie et biologic mol6culaire / Elsevier, Paris 815 …

Messenger RNA decay during aging and development

G Brewer - Ageing research reviews, 2002 - Elsevier
Gene expression is a combination of many processes, including transcription, pre-mRNA
processing, nucleocytoplasmic transport of mRNA, translation, mRNA decay, and protein …