Dexamethasone (DEX) is a synthetic glucocorticoid with potent anti-inflammatory effects that
is widely used to treat inflammatory diseases. The aim of the present study was to …

Background and objective: The major causes of mortality among patients who survive acute
lung injury/ARDS (ALI/ARDS) are due to the extensive tissue remodelling and fibrosis. Use …

The aim of this study is to investigate the effects of dexpanthenol in a model of acute lung
injury (ALI) induced by lipopolysaccharides (LPS). Lung injury was induced by exposure to …

Acute lung injury (ALI) is a serious complication of sepsis and an important cause of death in
intensive care. Studies have shown that DEX can inhibit inflammation. However, the anti …

Acute lung injury (ALI) and its severe manifestation of acute respiratory distress syndrome
(ARDS) are well-known illnesses. Uncontrolled and self-amplified pulmonary inflammation …

Background Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are
severe inflammatory lung diseases. Methylprednisolone (MP) is a common drug against …

Dexmedetomidine (Dex) is widely used for sedation in intensive care units and can be used
as an adjunct to anesthetics. Previous studies have demonstrated that Dex has anti …

The production of inflammatory mediators by epithelial cells in inflammatory lung diseases
may represent an important target for the anti-inflammatory effects of glucocorticoids …

CDDO-Me, initiated in a phase II clinical trial, is a potential useful therapeutic agent for
cancer and inflammatory dysfunctions, whereas the therapeutic efficacy of CDDO-Me on …

This study investigated the protective effect and underlying mechanism of action of
umbelliferone (Umb) against lipopolysaccharide (LPS)-induced acute lung injury (ALI). An …