Tracking a bolus of contrast agent traveling through the cerebral vasculature provides a
measure of the blood flow velocity in the respective cerebral tissue. This principle has been …

We present results of a clinical study on bedside perfusion monitoring of the human brain by
optical bolus tracking. We measure the kinetics of the contrast agent indocyanine green …

We present a minimally invasive optical method, that is, multi-channel time-domain diffuse
near-infrared reflectometry of the head to assess cerebral blood perfusion that is applicable …

Recently, it was shown in measurements carried out on humans that time-resolved near-
infrared reflectometry and fluorescence spectroscopy may allow for discrimination of …

We present a broad-band, continuous-wave spectral approach to quantify the baseline
optical properties of tissue and changes in the concentration of a chromophore, which can …

The aim of the study was to determine optimal measurement conditions for assessment of
brain perfusion with the use of optical contrast agent and time-resolved diffuse reflectometry …

Time-resolved diffuse optical methods have been applied to detect hemodynamic changes
induced by cerebral activity. We describe a near infrared spectroscopic (NIRS) …

It was reported that time-resolved reflectance measurements carried out during inflow and
washout of an optical contrast agent may provide information on the blood supply to the …

An optical technique based on diffuse reflectance measurement combined with indocyanine
green (ICG) bolus tracking is extensively tested as a method for the clinical assessment of …

Describes a simple method for measuring the'differential pathlength'of photons in a
scattering medium utilizing the spectral absorption features of water. Determination of this …