Recognition of DNA and RNA molecules derived from pathogens or self-antigen is one way
the mammalian immune system senses infection and tissue damage. Activation of immune …

Nucleic acid recognition is an important mechanism that enables the innate immune system
to detect microbial infection and tissue damage. To minimize the recognition of self-derived …

While the initiation of the adaptive and innate immune response is well understood, less is
known about cellular mechanisms propagating inflammation. The receptor for advanced …

The innate immune system forms the first line of protection against infectious and non-
infectious tissue injury. Cells of the innate immune system detect pathogen-associated …

The receptor for advanced glycation end products (RAGE) is a single transmembrane
receptor of the immunoglobulin superfamily that is mainly expressed on immune cells …

Mammalian Toll-like receptors (TLRs) are cellular pattern-recognizing receptors (PRRs) that
recognize the molecular patterns of pathogens. After engaging the pathogenic patterned …

The engagement of the receptor for advanced glycation end products (RAGE) on the cell
surface induces cellular dysfunction in a number of pathophysiological situations of vascular …

Streptococcus pneumoniae is the most common cause of community-acquired pneumonia.
The receptor for advanced glycation end products (RAGE) is a multiligand receptor that is …

Background The receptor for advanced glycation end products (RAGE) mediates a variety of
inflammatory responses Methods To determine the role of RAGE in the innate immune …

Pattern-recognition receptors have been highly conserved in evolution. They recognize
danger signals including both pathogen-and damage-associated molecular patterns, also …