Metabolism research is undergoing a renaissance because many diseases are increasingly
recognized as being characterized by perturbations in intracellular metabolic regulation …

Reversible O-phosphorylation of proteins is of central impor-tance to cell signaling in
eukaryotic systems. Protein phosphorylation may increase or decrease protein activity and …

Protein phosphorylation serves as a primary mechanism of signal transduction in the cells of
biological organisms. Technical advancements over the last several years in mass …

Phosphorylation of proteins is one of the most prominent PTMs and for instance a key
regulator of signal transduction. In order to improve our understanding of cellular …

Protein phosphorylation‐mediated signaling networks regulate much of the cellular
response to external stimuli, and dysregulation in these networks has been linked to multiple …

Phosphorylation is one of the most relevant and ubiquitous post-translational modifications.
Despite its relevance, the analysis of protein phosphorylation has been revealed as one of …

Protein phosphorylation is a post-translational modification (PTM) that orchestrates a diverse
array of cellular processes. Because this modification serves as a rapid and reversible …

There are likely more than 500000 potential phosphorylation sites in a cellular proteome.
This dynamic phosphorylation is under tight control of a variety of kinases and …

Phosphorylation, the reversible addition of a phosphate group to amino acid side chains of
proteins, is a fundamental regulator of protein activity, stability, and molecular interactions …

Recent advances in analytical methods, particularly in the area of mass spectrometry, have
brought the field of proteomics to the forefront in biological science. The ultimate goal of …