A robust SNP barcode for typing Mycobacterium tuberculosis complex strains

F Coll, R McNerney, JA Guerra-Assunção… - Nature …, 2014 - nature.com
Strain-specific genomic diversity in the Mycobacterium tuberculosis complex (MTBC) is an
important factor in pathogenesis that may affect virulence, transmissibility, host response …

High Resolution Discrimination of Clinical Mycobacterium tuberculosis Complex Strains Based on Single Nucleotide Polymorphisms

S Homolka, M Projahn, S Feuerriegel, T Ubben, R Diel… - PloS one, 2012 - journals.plos.org
Recently, the diversity of the Mycobacterium tuberculosis complex (MTBC) population
structure has been described in detail. Based on geographical separation and specific host …

Two New Rapid SNP-Typing Methods for Classifying Mycobacterium tuberculosis Complex into the Main Phylogenetic Lineages

D Stucki, B Malla, S Hostettler, T Huna, J Feldmann… - PloS one, 2012 - journals.plos.org
There is increasing evidence that strain variation in Mycobacterium tuberculosis complex
(MTBC) might influence the outcome of tuberculosis infection and disease. To assess …

Diversity and evolution of Mycobacterium tuberculosis: moving to whole-genome-based approaches

S Niemann, P Supply - Cold Spring …, 2014 - perspectivesinmedicine.cshlp.org
Genotyping of clinical Mycobacterium tuberculosis complex (MTBC) strains has become a
standard tool for epidemiological tracing and for the investigation of the local and global …

[HTML][HTML] PolyTB: a genomic variation map for Mycobacterium tuberculosis

F Coll, M Preston, JA Guerra-Assunção… - Tuberculosis, 2014 - Elsevier
Tuberculosis (TB) caused by Mycobacterium tuberculosis (Mtb) is the second major cause of
death from an infectious disease worldwide. Recent advances in DNA sequencing are …

Does M. tuberculosis genomic diversity explain disease diversity?

M Coscolla, S Gagneux - Drug Discovery Today: Disease Mechanisms, 2010 - Elsevier
The outcome of tuberculosis infection and disease is highly variable. This variation has been
attributed primarily to host and environmental factors, but better understanding of the global …

The Nature and Evolution of Genomic Diversity in the Mycobacterium tuberculosis Complex

D Brites, S Gagneux - Strain variation in the Mycobacterium tuberculosis …, 2017 - Springer
Abstract The Mycobacterium tuberculosis Complex (MTBC) consists of a clonal group of
several mycobacterial lineages pathogenic to a range of different mammalian hosts. In this …

Robust barcoding and identification of Mycobacterium tuberculosis lineages for epidemiological and clinical studies

G Napier, S Campino, Y Merid, M Abebe… - Genome medicine, 2020 - Springer
Background Tuberculosis, caused by bacteria in the Mycobacterium tuberculosis complex
(MTBC), is a major global public health burden. Strain-specific genomic diversity in the …

Ecology and evolution of Mycobacterium tuberculosis

S Gagneux - Nature Reviews Microbiology, 2018 - nature.com
Tuberculosis (TB) is the number one cause of human death due to an infectious disease.
The causative agents of TB are a group of closely related bacteria known as the …

Reference set of Mycobacterium tuberculosis clinical strains: A tool for research and product development

S Borrell, A Trauner, D Brites, L Rigouts, C Loiseau… - PLoS one, 2019 - journals.plos.org
The Mycobacterium tuberculosis complex (MTBC) causes tuberculosis (TB) in humans and
various other mammals. The human-adapted members of the MTBC comprise seven …